NEONATAL GASTROINTESTINAL PERFORATIONS | ||||
The Egyptian Journal of Surgery | ||||
Volume 19, Issue 2, April 2000, Page 78-86 PDF (950.29 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejsur.2000.378634 | ||||
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Authors | ||||
Essam A. Elhalaby* 1; Nagy I. Eldesoky1; Hamada H. Dawoud1; Ahmed F. Elsamongy2; Ahmed A. Darwish2; Mohamed A. Atia2; Moustafa Awny3; Manal E. Badwy4 | ||||
1Departments of Pediatric Surgery, Tanta University Hospital, Tanta , Egypt | ||||
2Departments of Surgery, Tanta University Hospital, Tanta , Egypt | ||||
3Departments of Pediatric, Tanta University Hospital, Tanta , Egypt | ||||
4Departments of Radiology, Tanta University Hospital, Tanta , Egypt | ||||
Abstract | ||||
Purpose: Neonatal gastrointestinal perforations continue to be associated with high morbidity and mortality rates. The aim of this study was to define causes, risk factors, and management of neonatal gastrointestinal perforations; and to analyze factors relevant to outcome. Methods: The medical records of 45 neonates treated at Tanta University Hospital for gastrointestinal perforations during the last 6 years were retrospectively reviewed. Results: Forty-five infants (25 males and 20 females) were analyzed. Their birth weight ranged from 1100 to 3500 grams (mean 2200 ± 750 grams). Perforations occurred from birth to 26 days (mean 10.5 days). Main causes of perforations included necrotizing enterocolitis (NEC) (21, 46.7%), spontaneous gastroduodenal perforation (5, 11%), iatrogenic colorectal perforations (4, 8.8%), spontaneous intestinal perforations (3, 6.6%), Hirschsprung’s disease (2, 4.4%), and meconium ileus (2, 4.4%). The terminal ileum and cecum were the most frequent sites of perforation. All patients underwent laparotmy except one patient, who died prior to surgical intervention. There were 19 deaths (42.2%). Nearly half of deaths (9, 47.4%) occurred in infants with NEC. Conclusions: 1: Septicemia, low birth weight, prematurity and delayed recognition of perforation were responsible for the majority of deaths in our series; 2: Although the overall mortality in this series compares favorably with similar other large series in the literature, there is still a room for improvement should iatrogenic perforations and delay in diagnosis be avoided: and 3: Simple closure for isolated perforations or resection and primary anastomosis is the treatment of choice, however, creation of stoma in some instances may be warranted. | ||||
Keywords | ||||
Gastrointestinal perforations; necrotizing enterocolitis; Neonatal peritonitis | ||||
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