SOME PHARMACOLOGICAL ASPECTS OF ULTRA-SHORT ACTING B-BLOCKER (ESMOLOL)
ATEF, M., AFIFI, N., RAMADAN, A., ALI, G. (1991). SOME PHARMACOLOGICAL ASPECTS OF ULTRA-SHORT ACTING B-BLOCKER (ESMOLOL). EKB Journal Management System, 39(1), 137-156. doi: 10.21608/vmjg.1991.379157
M. ATEF; NEHAL A. AFIFI; A. RAMADAN; G.M. ALI. "SOME PHARMACOLOGICAL ASPECTS OF ULTRA-SHORT ACTING B-BLOCKER (ESMOLOL)". EKB Journal Management System, 39, 1, 1991, 137-156. doi: 10.21608/vmjg.1991.379157
ATEF, M., AFIFI, N., RAMADAN, A., ALI, G. (1991). 'SOME PHARMACOLOGICAL ASPECTS OF ULTRA-SHORT ACTING B-BLOCKER (ESMOLOL)', EKB Journal Management System, 39(1), pp. 137-156. doi: 10.21608/vmjg.1991.379157
ATEF, M., AFIFI, N., RAMADAN, A., ALI, G. SOME PHARMACOLOGICAL ASPECTS OF ULTRA-SHORT ACTING B-BLOCKER (ESMOLOL). EKB Journal Management System, 1991; 39(1): 137-156. doi: 10.21608/vmjg.1991.379157

SOME PHARMACOLOGICAL ASPECTS OF ULTRA-SHORT ACTING B-BLOCKER (ESMOLOL)

Veterinary Medical Journal (Giza)
Volume 39, Issue 1, January 1991, Pages 137-156    PDF (13.91 M)
DOI: 10.21608/vmjg.1991.379157
Authors
M. ATEF* 1; NEHAL A. AFIFI1; A. RAMADAN1; G.M. ALI2
1Department of Pharmacology, Faculty of Veterinary Medicine. Cairo University, Giza, Egypt.
2Department of Anaesthesia, Faculty of Medicine, El-Azhar University.
Abstract
Esmolol is an ultra short-acting beta 1 adrenergic- receptor antagonist reported to have no intrinsic sympathomimetic activity. It has been successfully used in lowering the ventricular rate and rate-pressure product in patients with myocardial infarction, post myocardial infarction angina, or acute unstable angina (Kirshenbaum et al., 1985). In anaesthetized dogs, esmolol produced steady-state beta-blockade within 20 minutes of initiation of 3 hours i.v. infusions and did not produce alpha-blockade (Gorczynski and Vuons 1984). The aim of the present work is to investigate the effect of esmolol on some cardiovascular and respiratory functions. In addition. Its effect on duodenal and uterine smooth muscles was also studied.
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