Diastolic Pressure Dipping as a Predictor of Cardiovascular Complications in Patients with Obstructive Sleep Apnea

Elsanan, Moataz A.; Hassanin, Mesbah Taha; Maewad, Bishoy M.; Soliman, Mohammad H.; Kandeel, Nader T.; ElShora, Ashraf; Shehata, Islam E.

doi:10.21608/zumj.2024.314395.3544

	Diastolic Pressure Dipping as a Predictor of Cardiovascular Complications in Patients with Obstructive Sleep Apnea
Zagazig University Medical Journal
Article 12, Volume 30, Issue 8, November 2024, Page 4371-4383 PDF (762.73 K)
Document Type: Original Article
DOI: 10.21608/zumj.2024.314395.3544
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Authors
Moataz A. Elsanan¹; Mesbah Taha Hassanin¹; Bishoy M. Maewad ¹; Mohammad H. Soliman¹; Nader T. Kandeel ²; Ashraf ElShora³; Islam E. Shehata¹
¹Cardiology Department, Faculty of Medicine, Zagazig University, Egypt
²Department of Cardiology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
³Pulmonology Department, Faculty of Medicine, Zagazig University, Egypt
Abstract
Background: Evaluation of the predictive value of diastolic blood pressure; measured by ABPM, for cardiovascular complications in patients with OSA. Methods: This study included 62 patients already diagnosed with Obstructive sleep apnea. All the patients subjected to bedside trans-thoracicechocardiology, ambulatory blood pressure monitoring, resting ECG, Holter 24-hours ECG. Results: There was a positive association between the presence of DM, hypertension, BMI and ‎grades of OSA. ‎SPO2 was lower in patients with severe OSA than mild and moderate cases. ‎ ABPM 24h detected masked hypertension in approximately 45% of included patients. ‎ There was a positive correlation between night-time average diastolic BP and BMI, ‎hypertension, AHI, abnormal‏ ‏IVST, and diastolic dysfunction.‎ Regarding overall detected cardio-vascular complications, diastolic dysfunction was ‎detected in all patients. 65.6% had abnormal IVST, 40.625% had mild tricuspid ‎regurgitation, 18.75% had ischemia and 32.8% had AF. All patients with regional wall ‎motion abnormality had severe OSA. 91.7% of patients with Ischemic changes had ‎severe OSA. ‎Conclusion : ABPM 24h is considered a valuable tool in the detection of masked hypertension in non-dipper OSA patients. OSA is associated with a higher incidence of CVD that increases with increasing degree of OSA.
Keywords
Diastolic pressure; Complication; Obstructive sleep apnea


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