Comparison of agreement between the BioFire Film Array Pneumonia Panel and conventional culture-based methods in the diagnosis of bacterial pneumonia.
BENAISSA, E., belouad, E., benlahlou, Y., Maleb, A., chadli, M., elouennass, M. (2024). Comparison of agreement between the BioFire Film Array Pneumonia Panel and conventional culture-based methods in the diagnosis of bacterial pneumonia.. EKB Journal Management System, (), -. doi: 10.21608/mid.2024.315046.2169
ELMOSTAFA BENAISSA; elmehdi belouad; yassine benlahlou; Adil Maleb; mariama chadli; mostafa elouennass. "Comparison of agreement between the BioFire Film Array Pneumonia Panel and conventional culture-based methods in the diagnosis of bacterial pneumonia.". EKB Journal Management System, , , 2024, -. doi: 10.21608/mid.2024.315046.2169
BENAISSA, E., belouad, E., benlahlou, Y., Maleb, A., chadli, M., elouennass, M. (2024). 'Comparison of agreement between the BioFire Film Array Pneumonia Panel and conventional culture-based methods in the diagnosis of bacterial pneumonia.', EKB Journal Management System, (), pp. -. doi: 10.21608/mid.2024.315046.2169
BENAISSA, E., belouad, E., benlahlou, Y., Maleb, A., chadli, M., elouennass, M. Comparison of agreement between the BioFire Film Array Pneumonia Panel and conventional culture-based methods in the diagnosis of bacterial pneumonia.. EKB Journal Management System, 2024; (): -. doi: 10.21608/mid.2024.315046.2169

Comparison of agreement between the BioFire Film Array Pneumonia Panel and conventional culture-based methods in the diagnosis of bacterial pneumonia.

Microbes and Infectious Diseases
Articles in Press, Accepted Manuscript, Available Online from 14 September 2024
Document Type: Original Article
DOI: 10.21608/mid.2024.315046.2169
Authors
ELMOSTAFA BENAISSA* 1; elmehdi belouad1; yassine benlahlou1; Adil Maleb2; mariama chadli1; mostafa elouennass1
1Department of Clinical Bacteriology, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco
2Laboratory of Microbiology, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy (University Mohammed the First), Oujda, Morocco
Abstract
Background: Acute bacterial pneumonia is a bacterial infection of the lower respiratory tract caused by a bacterial agent. Diagnosis is delicate and depends on clinical, radiological and biological data. The aim of this study was to compare the agreement of the BioFire ® FilmArray ® Pneumonia Panel test with conventional methods used in the microbiological diagnosis of bacterial pneumonia. Methods: This was a retrospective study carried out in the bacteriology department. Samples were collected by conventional bacteriological methods and molecular methods using Biofire® FilmArray © Pneumonia panel. Results: The PN correctly detected all bacterial targets isolated by culture if the bacteria were included in the panel targets, with a positive agreement of 100%. Negative agreement ranged from 60 to 93%, and overall negative agreement was 79.6%.  Overall positive and negative concordance for the detection of strains harboring CTX-M, NDM and MecA/MecC/MREJ genes were 100.0% and 94% respectively. Conclusion: PN showed good agreement with culture methods nevertheless an interpretation correlated with culture data and clinico-radiological data would be judicious for a better management of these pathologies.
Keywords
Keywords: Pneumonia; BioFire FilmArray Pneumonia panel; concordance; conventional methods
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