Investigating Biochemical Biomarkers in Telogen Effluvium Post-COVID-19 Patients: A Retrospective Cohort Study | ||
| Journal of Bioscience and Applied Research | ||
| Volume 10, Issue 3, September 2024, Pages 593-599 PDF (865.1 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jbaar.2024.381597 | ||
| Authors | ||
| Ahmed Obaid Jasim* 1; Jinan Hameed Abu-Shana1; Jinan Ali Hussein2; Ekhlas Ali Hussein3; Muzahim Alkabban4 | ||
| 1Department of Chemistry and Biochemistry, College of Medicine, Al-Iraqia University, Baghdad, Iraq. | ||
| 2Ministry of Culture, Congress Palace Department, Baghdad, Iraq. | ||
| 3Department of Gynecology & Obstetrics, College of Medicine, Al-Iraqia University, Baghdad, Iraq. | ||
| 4Department of Dialysis Techniques, College of Health and Medical Technology, Albayan University, Baghdad, Iraq. | ||
| Abstract | ||
| Acute telogen effluvium (TE) represents a non-scaring form of hair loss that manifests approximately 3-months after a stressful incident. Notably, it relates to post-COVID-19 infections. This study aims to investigate the biochemical biomarkers associated with telogen effluvium in recovered COVID-19 patients. The study encompassed 108 participants, categorized by sex (64 male and 44 female) and age groups. Biochemical biomarkers were assessed, including complete blood count, liver enzymes, ferritin, D-dimer, and C-reactive protein (CRP) levels. Significant differences were revealed between males and females in terms of Hb levels, RBC, WBC, platelet, ESR, and CRP levels (p-value < 0.05). In addition to significant differences in D-dimer levels between age groups; lower mean values in age group 26-35 years and higher values observed at ≥ 46 years (p-value < 0.05). Additionally, significant correlations were found between D-dimer levels with LDH, CRP, and ferritin. The available evidence concludes that COVID-19 may lead to TE, a type of hair shedding, attributed to the stress induced by the infection. Sex disparities were noted in blood characteristics, with males exhibiting alterations in several parameters. D-dimer levels varied across different age groups. Persistently elevated D-dimer levels following a COVID-19 infection may be correlated with inflammatory markers. | ||
| Keywords | ||
| Biochemical Biomarkers; Hair Loss; Telogen Effluvium (TE); COVID-19 | ||
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