Relationship between Serum NT-ProBNP Level and Electrical Cardiometry in Monitoring Heart Failure Therapy | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 132, Volume 96, Issue 1, July 2024, Page 3244-3248 PDF (373.66 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2024.381748 | ||||
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| Abstract | ||||
| Background:Heart failure (HF) is a complex condition with a high death and hospitalization rate worldwide. Monitoring hospitalized patients receiving HF therapy is usually done by either invasive or non-invasive techniques. Nowadays more studies are focused on non-invasive techniques as they are easier and have fewer side effects. Objective: This study aimed to prove the relationship between electrical cardiometry fluid status measurements and serum NT-pro BNP levels in patients hospitalized for heart failure treatment. Methods:Fifty patients with chronic heart failure of both sexes over the age of 18 years participated in this prospective trial. Complete history taking, physical examination that included a general, cardiac, and chest examination, routine laboratory investigations and echocardiography evaluation were done for every patient. Assessment of congestion status based on the Everest congestion score, assessment of electrical cardiometry fluid status measurements (TFC and SVV) and NT-proBNP were evaluated for every patient twice, on time on admission and another before discharge after receiving optimal antifailure decongestion therapy. Results: The Everest congestion score, Thoracic fluid content (TFC) measured by electrical cardiometry (EC), and the serum NT-proBNP level were all significantly lower upon discharge than upon admission (P <0.001). The discharge results had a considerably larger stroke volume variation (SVV) than the admission (P<0.05). Serum NT-proBNP level and TFC at admission and discharge showed a positive correlation, while serum NT-proBNP level and SVV at admission and discharge showed a negative correlation (P value<0.05). Conclusions: EC can play a key role in monitoring the response to heart failure therapy via providing real time non-invasive objective assessment of fluid status throughTFC and SVV measurements, which showed strong correlation with NT proBNP levels and Everest congestion score. | ||||
| Keywords | ||||
| Electrical cardiometry; Everest congestion score; Fluid status assessment; Monitoring heart failure; Serum NT-proBNP level | ||||
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