Impact of Susceptibility Weighted MRI Sequences in Cerebral Small Vessel Disease | ||||
| Benha Journal of Applied Sciences | ||||
| Article 5, Volume 9, Issue 9, September 2024, Page 33-42 PDF (603.46 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2024.317619.1487 | ||||
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| Authors | ||||
Hisham Al-Sayed Al-Sheikh1; Alaa Adil Hamad  2; Mohamed Awaad Tawfik3
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| 1Professor of Radiodiagnosis, Faculty of Medicine, Benha University, Egypt | ||||
| 2Department of Radio diagnosis, Faculty of Medicine, Benha University, Egypt | ||||
| 3Lecturer of Diagnostic and Interventional Radiology, Faculty of Medicine, Benha University, Egypt | ||||
| Abstract | ||||
| Background: Brain microvascular disease (CSVD) is a multifactorial condition affecting the brain's arterioles, venules, capillaries, and microscopic arteries. Susceptibility-weighted imaging (SWI) is a fully velocity-compensated high-resolution 3D gradient-echo sequence that creates new contrast sources using magnitude and filtered-phase data. This study aimed to weighed MRI sequences for CSVD susceptibility evaluation. Methods: SVD patients with CSVD were studied in this prospective observational study. Every patient had a comprehensive clinical evaluation, routine laboratory testing, susceptibility weighted MRI (SWI), and determination of the plasma atherogenic index. Results: The stroke-to-MRI time was longer in patients with one or more vascular clusters (P=0.028). Radiological investigation revealed no significant difference in WMH scores, however patients with vascular clusters had bigger lacunes, PVH + DWMH Fazekas score, basal ganglia + centrum semiovale PVS score, and overall PVS score (P<0.05). In multivariate logistic regression, the only significant predictors of vessel-clusters were age, male sex, and lacune amount. Conclusion: It seems that vascular clusters might be useful in risk stratification and individualised treatment for lacunar stroke. To find out how vessel-clusters impact clinical outcomes over time, further research is required. | ||||
| Keywords | ||||
| Cerebral Small Vessel Disease; Sequences; Weighted MRI; Susceptibility | ||||
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