The impact of weight reduction following laparoscopic sleeve gastrectomy on thyroid-stimulating hormone level in obese patients with subclinical hypothyroidism: A 3-year retrospective study | ||||
| The Egyptian Journal of Surgery | ||||
| Volume 43, Issue 4, October 2024, Page 1501-1505 PDF (270.48 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/EJSUR.2024.295763.1095 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Sherif A. Saber; Tamer M. Elmahdy; Sherif Elgarf; Ahmed H. Amer; Ahmed Swelam; Gamal Mousa; Amr S. Ghobara; Mahmoud A. Eissa* | ||||
| Department of General Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt | ||||
| Abstract | ||||
| Background: The effect of weight-reducing surgeries on thyroid function in morbid obese patients was evaluated by several studies. However, because of the variability of the techniques and the degrees of hypothyroidism, their results were inconsistent. So, our aim in this study was to evaluate the effect of laparoscopic sleeve gastrectomy (LSG) on thyroid function in obese patients with subclinical hypothyroidism (SH) seeking weight reduction as it is considered the most common weight-reducing surgery performed and compare its results with malabsorptive procedures. Patients and Methods: This is a retrospective study evaluating all obese patients that underwent different weightreducing procedures with a preoperative diagnosis of SH from June 2020 to June 2023, evaluating the thyroid function in obese patients after surgery. Results: One hundred thirty-four (9.3%) out of the 1450 morbidly obese patients that underwent LSG (82/813), Rouxen- Y gastric bypass (RYGB) (41/397) and mini-gastric bypass (MGB) (11/240) during the study period were found to have SH during the preoperative investigations. Hypothyroidism improved in 50 (60.9%) patients and completely resolved in 20 (24.3%) patients, while 11 (13.4%) patients experienced no improvement, and one (1.4%) patient developed overt hypothyroidism following LSG after 1 year of follow up. Hypothyroidism improved in 16 (39%) patients and completely resolved in 23 (56%) patients, while two (5%) patients experienced no improvement following RYGB after 1 year of follow-up. Hypothyroidism improved in four (36.3%) patients and completely resolved in six (54.5%) patients, while one (9.2%) patient experienced no improvement following MGB after 1 year of follow-up. The mean excess weight loss after 1 year of surgery was 43.7% after LSG, 49.2% after RYGB, and 50.1% after MGB. Conclusion: Obesity itself has a significant impact on thyroid function, and different bariatric surgeries produce a significant improvement of SH. | ||||
| Keywords | ||||
| Bariatric; hypothyroidism; sleeve | ||||
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