Incidence and risk factors of low anterior resection syndrome with validation of low anterior resection syndrome score questionnaire among the Egyptian patients | ||||
The Egyptian Journal of Surgery | ||||
Volume 43, Issue 4, October 2024, Page 1511-1519 PDF (398.68 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/EJSUR.2024.296025.1097 | ||||
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Authors | ||||
Reham Zakaria ![]() ![]() | ||||
Department of General Surgery, Faculty of Medicine, Zagazig University, Zagazig, Sharqia, Egypt | ||||
Abstract | ||||
Background: Since the priority for patients with rectal tumors is a complete cure from the disease with free safety margins for tumor removal and complete control of systemic disease, postoperative squeals, which may last for life, have been overlooked. It was important to study the quality of life after surgery and chemoradiotherapy, especially the impact on bowel functions, in order to improve them and give psychological support to the patient. Patients and Methods: This is a single-center prospective cohort study held in the Surgery Department from December 2017 to December 2022. It included 120 patients who had surgery for rectal tumors. Only patients who filled out the low anterior resection syndrome (LARS) score questionnaire, which was correlated to scores of the three subscales of EORTC QLQ-C30 v3 (The European Organisation for Research and Treatment of Cancer-Quality of Life Questionnaire Core 30 version3), were included. Results: One hundred twenty patients were included, 40 patients had no LARS, 45 patients had minor LARS, and 35 patients had major LARS. LARS score was highly significantly higher with a P value less than 0.001 in patients with old age, high BMI, low rectal and T4 tumors, open surgery, hand-sewn coloanal anastomosis, intersphincteric resection surgery, total mesorectal excision, patients who had neoadjuvant and adjuvant therapy. Conclusion: The LARS questionnaire is a valid and reliable tool to evaluate LARS among Egyptian patients. Risk factors of discrimination can be found in those patients. | ||||
Keywords | ||||
Anterior resection; diarrhea; low anterior resection syndrome; rectal tumors | ||||
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