EFFECT OF CHLORTETRACYCLINE AS A GROWTH PROMOTER AND LEVAMISOLE ON THE IMMUNE RESPONSE OF CHICKENS AGAINST NEWCASTLE DISEASE VACCINE
SAID, N., ABDEL-KHALIK GAMMAZ, H., HASSAN, M., ELSHAZLY, D. (2005). EFFECT OF CHLORTETRACYCLINE AS A GROWTH PROMOTER AND LEVAMISOLE ON THE IMMUNE RESPONSE OF CHICKENS AGAINST NEWCASTLE DISEASE VACCINE. EKB Journal Management System, 53(2), 311-328. doi: 10.21608/vmjg.2005.384703
NAGWA, A SAID; H ABDEL-KHALIK GAMMAZ; M HASSAN; DALIA, A ELSHAZLY. "EFFECT OF CHLORTETRACYCLINE AS A GROWTH PROMOTER AND LEVAMISOLE ON THE IMMUNE RESPONSE OF CHICKENS AGAINST NEWCASTLE DISEASE VACCINE". EKB Journal Management System, 53, 2, 2005, 311-328. doi: 10.21608/vmjg.2005.384703
SAID, N., ABDEL-KHALIK GAMMAZ, H., HASSAN, M., ELSHAZLY, D. (2005). 'EFFECT OF CHLORTETRACYCLINE AS A GROWTH PROMOTER AND LEVAMISOLE ON THE IMMUNE RESPONSE OF CHICKENS AGAINST NEWCASTLE DISEASE VACCINE', EKB Journal Management System, 53(2), pp. 311-328. doi: 10.21608/vmjg.2005.384703
SAID, N., ABDEL-KHALIK GAMMAZ, H., HASSAN, M., ELSHAZLY, D. EFFECT OF CHLORTETRACYCLINE AS A GROWTH PROMOTER AND LEVAMISOLE ON THE IMMUNE RESPONSE OF CHICKENS AGAINST NEWCASTLE DISEASE VACCINE. EKB Journal Management System, 2005; 53(2): 311-328. doi: 10.21608/vmjg.2005.384703

EFFECT OF CHLORTETRACYCLINE AS A GROWTH PROMOTER AND LEVAMISOLE ON THE IMMUNE RESPONSE OF CHICKENS AGAINST NEWCASTLE DISEASE VACCINE

Veterinary Medical Journal (Giza)
Volume 53, Issue 2, April 2005, Page 311-328  XML PDF (5.8 MB)
Document Type: Original Article
DOI: 10.21608/vmjg.2005.384703
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Authors
NAGWA, A SAID* 1; H ABDEL-KHALIK GAMMAZ2; M HASSAN2; DALIA, A ELSHAZLY3
1Immunology Dept.,Animal Health Research Institute, Dokki
2Pharmacology Dept., Faculty of Vet. Medicine, Suez Canal University
3Biochemistry Dept., Animal Health Research Institute, IsmailIa, Egypt
Abstract
310 one day old Ross chicks were used to study the effect of Chlortetracycline as a growth promoter (200 gm/ton ration) and/or Levamisole (20 mg/kg b.w.} on the immune response of chickens either non-vaccinated or vaccinated against New- castle disease virus. Chlortetracycline was found to increase the body weight and food consump­tion, and to improve the feed conversion ratio and feed effeciency, but it decreased the cellular immune response represented by decreased lYmphocyte stimulation index against phytoheamagglutinin, phagocytosis percentage and phago­cytic index. Also, it decreased the humoral immune response represented by decreased anti­body titre (ELISA titre) and decreased protection rate of the Newcastle vaccine against challenge with virulent ND • virus. While, levamisole in­ creased all the parameters of the cellular and humoral immune response in the chickens treated with both chlortetracycline and levamisole, thus assuring the levamisole immunorestorative properties
Keywords
Chlortetracycline; Levamisole; Immune response; Immunosuppression; Immunomodulator; chickens
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