PREPARATION OF INACTIVATED INFECTIOUS BRONCHITIS VIRUS DISEASE VACCINE USING NEW OIL ADJUVANT PRIVATE
AMAL, I., DAOUD, A., EL-BOURDINY, F. (2005). PREPARATION OF INACTIVATED INFECTIOUS BRONCHITIS VIRUS DISEASE VACCINE USING NEW OIL ADJUVANT PRIVATE. EKB Journal Management System, 53(2), 329-339. doi: 10.21608/vmjg.2005.384705
I AMAL; A DAOUD; FEKRIA EL-BOURDINY. "PREPARATION OF INACTIVATED INFECTIOUS BRONCHITIS VIRUS DISEASE VACCINE USING NEW OIL ADJUVANT PRIVATE". EKB Journal Management System, 53, 2, 2005, 329-339. doi: 10.21608/vmjg.2005.384705
AMAL, I., DAOUD, A., EL-BOURDINY, F. (2005). 'PREPARATION OF INACTIVATED INFECTIOUS BRONCHITIS VIRUS DISEASE VACCINE USING NEW OIL ADJUVANT PRIVATE', EKB Journal Management System, 53(2), pp. 329-339. doi: 10.21608/vmjg.2005.384705
AMAL, I., DAOUD, A., EL-BOURDINY, F. PREPARATION OF INACTIVATED INFECTIOUS BRONCHITIS VIRUS DISEASE VACCINE USING NEW OIL ADJUVANT PRIVATE. EKB Journal Management System, 2005; 53(2): 329-339. doi: 10.21608/vmjg.2005.384705

PREPARATION OF INACTIVATED INFECTIOUS BRONCHITIS VIRUS DISEASE VACCINE USING NEW OIL ADJUVANT PRIVATE

Veterinary Medical Journal (Giza)
Volume 53, Issue 2, April 2005, Page 329-339  XML PDF (3.33 MB)
Document Type: Original Article
DOI: 10.21608/vmjg.2005.384705
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Authors
I AMAL* 1; A DAOUD2; FEKRIA EL-BOURDINY2
1Central Laboratory for Evaluation of Veterinary Biologics, Abbasia, Cairo.
2Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo.
Abstract
Montanide ISA 50 was used as an adjuvant for preparation of inactivated IB vaccines and com-pared with commercially available inactivated LB vaccine adjuvanted with paraffin oil. The vaccine was tested for safety and potency. Serological tests were carried out to follow up the immune status post vaccination by using serum neutralization test and ELISA test for 6 months post vaccination. The results indicated that the vaccine prepared with Montanide ISA-50 oil adjuvant appeared to be more potent and gave protective level reached up to 6 months in comparison with the commercially used vaccine contained paraffin oil gave protection until 4 months only.
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