Pathological and clinic-pathological studies on the effects of potassium bromate in selected organs of albino rat | ||
| Veterinary Medical Journal (Giza) | ||
| Volume 61, Issue 4, October 2015, Pages 9-20 PDF (4.08 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/vmjg.2015.385476 | ||
| Authors | ||
| El-Mahdy M* 1; Bakeer M1; Gad G2; Abouzzon A2 | ||
| 1Department of Pathology, Faculty of Veterinary Medicine, Cairo University | ||
| 2Department of Tissue and cell, Faculty of Veterinary Medicine, Cairo University | ||
| Abstract | ||
| The presentt study was conducted to investigate the toxic effects of various levels of potassium bromsate in male and female rats. The criteria for assessment include its effects on the pathological and haematological alterations. A total number of 105 albino rats of both sexes, weighing 120 g were used in this experment. The animal used were 45 male, 45 female, and 15 rats of both sexes used as control. Both male and female rats were divided into three groups, The animals were left for a week as an adaptation period. KBrO3 dissolved in water at concentrations of 200, 400 and 666 ppm respectively and administrated to male and female group rats daily till the end of the experiment. After 6, 9, and 14 months ten animals from each group (5 male and 5 female) and five from the control were sacrificed by servical dislocation. Blood samples and tissee specimens were collected for haematological and histological examination. Heamatological results revealed significant variations of most of the different estimated parameters except monocytes and eosinophils as compared with the control group. | ||
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