The Effect of Low-Fat Diet on Absorption of Fat-Soluble Vitamins in Dyslipidemic Children (Age From 6-12 Years) | ||
| المجلة العلمية للتربية النوعية والعلوم التطبيقية | ||
| Volume 7, Issue 21, July 2024, Pages 132-162 PDF (402.17 K) | ||
| DOI: 10.21608/sjseas.2024.385692 | ||
| Authors | ||
| Somaya Abo Elnaga Youssif* 1; Ashraf Abd El Aziz Abd El-Megeid* 2; Hanaa Hussein Elsayed* 3; Mary Shaker Zakher Gerges* 4 | ||
| 1Bachelor’s degree in economics (Major Nutrition and Food Science), Home Economics, Helwan University, Dietitian at Cairo University children Hospital. | ||
| 2Professor of Nutrition, Nutrition and Food Science Department Former Dean of Faculty of Home Economics Helwan University | ||
| 3Prof. Environmental Science for Nutritional Chemistry and Metabolism, National Nutrition Institute | ||
| 4Pediatric Clinical Nutrition Consultant, Cairo University Fellow of Pediatric (GOTHI) | ||
| Abstract | ||
| Background: Dyslipidemia in children is associated with abnormal lipid metabolism and an increased risk of cardiovascular disease. This study investigates the serum levels of fat-soluble vitamins A, E, and D, and determines the prevalence of deficiencies in children with dyslipidemia following a low-fat diet. Methods: The study, conducted at Cairo University Children Hospital between September 2022 and October 2023, included 35 children aged 6-12 years diagnosed with dyslipidemia. These children adhered to the CHILD-2-LDL diet for over 6 months. Demographic data, anthropometric measurements, dietary intake, and serum lipid profiles were collected. Serum levels of vitamins A, E, and D were measured using HPLC and immunoassay methods. Results: The dyslipidemia group included 16 males (45.7%) and 19 females (54.3%), with a mean age of 10 years. The lipid profile showed total cholesterol (364.1 ± 198 mg/dl), LDL cholesterol (225.6 mg/dl), and triglycerides (368.1 mg/dl), and HDL cholesterol (36.8 ± 25.2 mg/dl). Vitamin D levels were significantly low (15.7 ± 5.7 ng/ml), indicating a deficiency. While vitamin A and E levels were within normal ranges, dyslipidemia patients exhibited a trend toward low vitamin A levels. Conclusion: Children with dyslipidemia demonstrated significant lipid abnormalities and vitamin D deficiency. These findings underscore the importance of dietary interventions and supplementation to address nutritional deficiencies and improve lipid profiles, thereby reducing cardiovascular risks in pediatric dyslipidemia patients. | ||
| Keywords | ||
| low Fat Diet; Dyslipidemia; Fat Soluble Vitamins; Lipids; Vit. A; Vit. D; Vit. E; Pediatrics | ||
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