"Evaluation of Antioxidant, Anti-Inflammatory, and Anticancer Activities of Palm Heart (Phoenix dactylifera L.) In Vitro" | ||||
| Journal of Food and Dairy Sciences | ||||
| Article 1, Volume 15, Issue 9, September 2024, Page 123-132 PDF (666.19 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jfds.2024.311382.1163 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Mona Y. Mostafa  
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| Home Economics Department (Nutrition and Food Science), Faculty of Specific Education, Mansoura University, Mansoura, Egypt. | ||||
| Abstract | ||||
| This study assessed the chemical composition of palm hearts (P. dactylifera, var., Zaghloul), locally called "Al-Guomar," and their ethanolic extract's effect as an antioxidant, anti-inflammatory, and anticancer in vitro using Hela and Mcf7 breast cancer cells. Palm hearts were high in fiber, protein, and carbohydrates. The extract contained 37.7 mg QE/g of total flavonoids and 79.6 mg GAE/g of total phenols. Using the 1,1-diphenyl-2-picryl hydrazyl (DPPH) test, the antioxidant activity of the ethanolic extract was determined. DPPH scavenging activity was maximum at 73.19% and 67.68%, respectively, for the extract concentrations of 1000 µg/mL and 500 µg/mL, whereas the IC50 value was 73.97 µg /ml. Because the ethanolic extract significantly decreased red blood cell hemolysis, it had an anti-inflammatory impact. At 1000 µg/mL, the maximum percentage of inhibition was achieved, which was 93.9%. In human cell lines of breast cancer (Mcf7) and cervical cancer (Hela), the extract lowered cells' viability in a concentration-dependent manner. Compared to the control, it also significantly altered the morphology of the cells. Therefore, it is recommended that palm heart "Goumar" be consumed either fresh or in food products to prevent some cancers. | ||||
| Keywords | ||||
| palm heart; anticancer; anti-inflammatory; breast cancer; cervical cancer | ||||
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