Prognostic and Diagnostic Value of Pancreatic Stone Protein (PSP) in Septic Intensive Care Unit (ICU) Patients | ||
| Aswan University Medical Journal | ||
| Article 8, Volume 4, Issue 3, December 2024, Pages 74-83 PDF (875.44 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aumj.2024.324206.1139 | ||
| Authors | ||
| Eman abdallah mahmoud* ; Emad Farah Kholef; Mahmoud Gamal Elagramy | ||
| Department of Clinical Pathology, faculty of medicine, Aswan University | ||
| Abstract | ||
| Background: Sepsis is a condition caused by the dysregulation of the host response to infection, and known as life-threatening organ dysfunction. Aim: To estimate of the pancreatic stone protein level in intensive care unit septic manifestation and prognostic and diagnostic value of pancreatic stone protein. Patients and methods: This prospective case control research has been performed at Aswan University Hospital. Results: Pearson’s correlation coefficients (r) between procalcitonin level and C- reactive protein (CRP) was 0.348, with a strong positive relationship between the two variables. Pearson’s correlation coefficients (r) between procalcitonin level and blood culture (positive) were 0.197, with a strong positive relationship between the two variables. Pearson’s correlation coefficients (r) between pancreatic stone protein level and blood culture (positive) were -0.098, with a weak negative relationship between the two variables. Conclusion: Procalcitonin is a reliable predictor of mortality and a marker for sepsis, while pancreatic stone protein is limited in critically sick cases for diagnosing sepsis, but its performance is comparable to other biomarkers like CRP and PCT. | ||
| Keywords | ||
| Procalcitonin; CRP; Pancreatic stone protein | ||
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