The Effect of preoperative nebulized: Magnesium sulfate versus lidocaine on the prevention of post-intubation sore throat | ||||
| Egyptian Journal of Anaesthesia | ||||
| Volume 36, Issue 1, January 2020, Page 1-6 PDF (746.01 K) | ||||
| DOI: TEJA-2020-0007 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Alshaimaa Abdel Fattah Kamel; Olfat Abdelmoniem Ibrahem Amin | ||||
| Abstract | ||||
| : Different agents have been used to control postoperative sore throat after general anesthesia with variable success. The aim of this study was to compare the effect of preoperative-nebulized magnesium sulfate versus lidocaine on the prevention of post-intubation sore throat. : A prospective double-blind randomized controlled study. Seventy-eight8 patients were divided randomly into three equal groups: Group (M) ( = 26): received nebulized magnesium sulfate 250 mg (2.5 ml) plus 2.5 ml normal saline. Group (L) ( = 26): received nebulized lidocaine 2% 100 mg (5 ml). Group (C) ( = 26): received nebulized normal saline 5 ml. So total volume (5 ml). Patients nebulized by compressor nebulizing for 15 min before the induction of anesthesia. s: At 0 and 2 h postoperative, the severity and incidence of sore throat were statistically significantly lower in group M and L compared to the C group ( < 0.001). However, at the same time interval, both groups M and L were comparable ( > 0.05). At 4, 8, 12, 24 h postoperative, the severity and incidence of sore throat were statistically significantly lower in group M compared to L and C groups ( < 0.001). However, at the same time interval, both groups L and C were comparable ( > 0.05). The hemodynamics was statistically significantly reduced in group L compared to M and C groups. However, group M showed statistically insignificant changes in hemodynamics compared to groups L and C. : Preoperative 250 mg nebulized magnesium sulfate has more protection against post-intubation sore throat than 100 mg nebulized lidocaine lasting up to 24 h after the operation. | ||||
| Keywords | ||||
| Sore throat; magnesium sulfate; lidocaine and post-intubation | ||||
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