A study of menstrual cycle effects on pain perception, haemodynamic response to laryngoscopy, and postoperative outcome in gynaecological laparoscopy | ||||
Egyptian Journal of Anaesthesia | ||||
Volume 38, Issue 1, December 2022, Page 680-693 PDF (1.13 MB) | ||||
DOI: TEJA-2022-0194 | ||||
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Authors | ||||
Mariam Hanna Mossad Samaan; Tarek Mohamed Ahmed Sarhan; Ramadan Abd El Azim Ammar; Tamer Hanafy Mahmoud; Ahmed Mohamed Ahmed El Shafie | ||||
Abstract | ||||
Background The physiological alterations that occur during the females’ reproductive age due to hormonal fluctuations throughout the menstrual cycle may affect the perioperative period and impact the postoperative outcome. This study evaluated the impact of menstrual cycle phases on pain perception, haemodynamic response to laryngoscopy, postoperative agitation, nausea, and vomiting in women undergoing laparoscopic gynaecological procedures. Methods This prospective observational study included 60 women who were randomly assigned to have diagnostic gynaecological laparoscopy during their menstrual cycle’s luteal or follicular phases. Patients were divided into two groups: follicular and luteal group. Preoperatively a blood sample was withdrawn for measurement of norepinephrine, estradiol, and progesterone levels. Anaesthetic techniques were standardized in both groups. In the postoperative period, another blood sample was withdrawn from all patients and sent for norepinephrine measurement. Results Women in the follicular phase showed higher postoperative pain, higher incidence of postoperative nausea, and more increase in HR and delayed return to baseline value post tracheal intubation as compared to luteal phase. | ||||
Keywords | ||||
menstrual cycle; Postoperative Pain; Postoperative nausea and vomiting; norepinephrine; haemodynamic response to laryngoscopy; postoperative agitation | ||||
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