The effect of ondansetron in preventing the hypotensive bradycardic events during shoulder arthroscopy done under interscalene block in the sitting position | ||||
Egyptian Journal of Anaesthesia | ||||
Volume 30, Issue 3, July 2014, Page 305-310 PDF (482.28 K) | ||||
DOI: 10.1016/j.egja.2014.02.002 | ||||
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Authors | ||||
Riham Hasanein; Wael El-Sayed | ||||
Abstract | ||||
Purpose This study was conducted to test whether blocking the serotonin receptors by intravenous [IV] ondansetron; can help in reducing the hypotensive bradycardic events [HB events] associated with shoulder arthroscopy done in the sitting position under interscalene plexus block [ISB]. Methods One hundred and fifty patients, scheduled for shoulder arthroscopy in the sitting position under ISB, were randomly assigned to one of three groups receiving either: 4 mg ondansetron, or 8 mg ondansetron or saline. Results IV injection of ondansetron 4 mg or 8 mg significantly reduced the incidence of HB events from 20.4% in the saline group to 6.1% after injection of 4 mg ondansetron and 6% after injection of 8 mg ondansetron; value [0.030]. Conclusion IV ondansetron either 4 mg or 8 mg reduces the HB events during shoulder arthroscopy in the sitting position under ISB. | ||||
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