A study of Non-Cultured Epidermal Suspension Grafting Using Trypsinized Epidermal Grafting for Stable Vitiligo | ||
| Zagazig University Medical Journal | ||
| Volume 31, Issue 1, January 2025, Pages 76-83 PDF (659.11 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2024.328961.3647 | ||
| Authors | ||
| Samia A. Ibrahim1; Sara Mohamed Ibrahim Mohamed* 2; Khaled Gharib3 | ||
| 1Professor of Dermatology ,Veneroleogy and Andrology, Faculty of Medicine, Zagazig University, Egypt | ||
| 2Dermatology, Venerology & Andrology Department, Faculty of Medicine, Zagazig University, Egypt | ||
| 3Professor of Dermatology , Veneroleogy and Andrology, Faculty of Medicine, Zagazig University, Egypt | ||
| Abstract | ||
| Background: The loss of functioning melanocytes and a dysregulated immune system lead to the persistent depigmenting illness known as vitiligo. The objective of this research was to examine the efficacy of Noncultured epidermal suspension (NCES) transplantation as a therapy for persistent vitiligo. Methods: The investigation was a clinical trial. There were twenty-four patients with stable vitiligo. The degree of repigmentation and color match were assessed 16 weeks after surgery. Results: The percentage of improvement in NCES group, on 8 days, 2 (8.33%) patients had been improved with an improvement percentage of 2%, after 4 weeks 16 (66.67%) patients had been improved with an improvement percentage of 10%, after 8 weeks 14 (58.33%) patients had been improved with an improvement percentage of 30%, after 12 weeks and after 16 weeks, the studied patients showed stable improvement where 12 (50%) patients in both times had been improved with an improvement percentage of 62%. Conclusions: For individuals with stable vitiligo, NCES is the recommended course of treatment due to its great effectiveness. the rate of repigmentation was high in NCES. | ||
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| Conflict of interest: The authors declare no conflict of interest. Financial Disclosures: This study was not supported by any source of finding. Sources of funding: No specific grant was obtained for this research from governmental; private; or nonprofit funding organizations | ||
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