COVID-19 in geriatric population: Prevalent symptoms and risky parameters
Maher, R., Afify, S., Shousha, H., El-Kassas, M., Asem, N., Fouad, E., Bahbah, E., Mostafa, N., Mostafa, E., Medhat, M., Abdelazeem, A., Elmorsy, H., Mohammed, R., Essa, B., Abdel Wahab, S., Salah, N., Elawady, B. (2025). COVID-19 in geriatric population: Prevalent symptoms and risky parameters. EKB Journal Management System, 6(1), 1-11. doi: 10.21608/mid.2024.304244.2091
Rabab Maher; Shimaa Afify; Hend Shousha; Mohamed El-Kassas; Noha Asem; Eman Fouad; Eshak Bahbah; Nermin Zaky Mostafa; Ehab Mostafa; Mohammed Medhat; Amr Abdelazeem; Hazem Elmorsy; Rateba Mohammed; Basem ELsayed Essa; Sabrin Abdel Wahab; Nagwa Salah; Basma Ahmed Elawady. "COVID-19 in geriatric population: Prevalent symptoms and risky parameters". EKB Journal Management System, 6, 1, 2025, 1-11. doi: 10.21608/mid.2024.304244.2091
Maher, R., Afify, S., Shousha, H., El-Kassas, M., Asem, N., Fouad, E., Bahbah, E., Mostafa, N., Mostafa, E., Medhat, M., Abdelazeem, A., Elmorsy, H., Mohammed, R., Essa, B., Abdel Wahab, S., Salah, N., Elawady, B. (2025). 'COVID-19 in geriatric population: Prevalent symptoms and risky parameters', EKB Journal Management System, 6(1), pp. 1-11. doi: 10.21608/mid.2024.304244.2091
Maher, R., Afify, S., Shousha, H., El-Kassas, M., Asem, N., Fouad, E., Bahbah, E., Mostafa, N., Mostafa, E., Medhat, M., Abdelazeem, A., Elmorsy, H., Mohammed, R., Essa, B., Abdel Wahab, S., Salah, N., Elawady, B. COVID-19 in geriatric population: Prevalent symptoms and risky parameters. EKB Journal Management System, 2025; 6(1): 1-11. doi: 10.21608/mid.2024.304244.2091

COVID-19 in geriatric population: Prevalent symptoms and risky parameters

Microbes and Infectious Diseases
Article 1, Volume 6, Issue 1, February 2025, Page 1-11  XML PDF (335.76 K)
Document Type: Original Article
DOI: 10.21608/mid.2024.304244.2091
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Authors
Rabab Maherorcid 1; Shimaa Afifyorcid 2; Hend Shoushaorcid 3; Mohamed El-Kassasorcid 4; Noha Asemorcid 5, 6; Eman Fouadorcid 5; Eshak Bahbahorcid 7; Nermin Zaky Mostafa email orcid 8; Ehab Mostafaorcid 9; Mohammed Medhatorcid 9; Amr Abdelazeemorcid 4; Hazem Elmorsyorcid 10; Rateba Mohammedorcid 11; Basem ELsayed Essaorcid 12; Sabrin Abdel Wahab1; Nagwa Salah13; Basma Ahmed Elawadyorcid 8
1Students Hospital, Cairo University, Giza, Egypt
2Gastroenterology Department, National Hepatology & Tropical Medicine Research Institute, Cairo, Egypt
3Endemic Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt
4Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt
5The Public Health Department, Faculty of Medicine, Cairo University, Cairo, Egypt
6Egyptian Ministry of Health and Population, Cairo, Egypt
7Faculty of Medicine, Al-Azhar University, Damietta, Egypt
8Medical Microbiology and Immunology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
9Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assuit, Egypt
1015 Mayo Smart Hospital, Ministry of Health and Population, Cairo, Egypt
11Occupational and Environmental Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt
12Gastroenterology Department, National Hepatology & Tropical Medicine Research Institute, Cairo, Egypt
13Clinical Pathology National Hepatology and Tropical Medicine Research Institute, Egypt
Abstract
Background: Geriatric patients with Coronavirus Disease 2019 (COVID-19) are prone to severe acute respiratory syndrome. Hepatic and gastrointestinal tract affections have been recognized with variable severity.  Aim: to assess risk factors, clinical features, and laboratory parameters of COVID-19 infection and outcomes in elderly patients. Methods: A multicenter cohort study was carried out from April to July 2020 on COVID-19-positive cases confirmed by polymerase chain reaction (PCR). Data was gathered from four quarantine hospitals connected to the Egyptian Ministry of Health. Records included demographics, laboratory results, the patient's outcome, and therapy. Results: Our study was conducted on 80 geriatric patients/547 COVID-19 patients, of whom 20 died during hospitalization, 59 were recovered, and one lost to follow-up. The elderly age group was associated with elevation of aspartate transaminase (AST), ferritin, creatinine, and urea with decline in serum albumin, and estimated glomerular filtration rate (eGFR). Analysis for factors affecting survival among the elderly age group revealed mild and moderate COVID-19 disease; normal urea level; and factors associated with increased mortality (lung consolidation; intensive care unit (ICU) admission; critical COVID-19 disease. Elevated AST or alanine transaminase (ALT) levels are linked to several variables, including lung involvement, smoking, hypertension, chronic hepatitis C, and male gender. Fibrosis-4 score (FIB-4) was higher in ICU patients. Among 80 patients with gastrointestinal symptoms, 5 patients had diarrhea. Additionally, elderly patients had fever, dyspnea, sore throat, headache, and dry cough. Conclusion: Compared to GIT symptoms, pulmonary symptoms were more prevalent in elderly people with COVID-19 illness, with a higher risk of critical illness and death.
Keywords
COVID-19; Elderly; hepatorenal dysfunction; Gastrointestinal symptoms; Fibrosis-4
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