The study of antimicrobial activity and molecular dockingsimulation of treated cotton fabric with fire retardancy phosphorous-PMMA/modified MMT nanocomposites | ||||
| Journal of Basic and Environmental Sciences | ||||
| Volume 11, Issue 4, October 2024, Page 390-407 PDF (2.74 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jbes.2024.391117 | ||||
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| Authors | ||||
| Osama A. Goda1; Mohamed N. Ismail2; Naglaa M. Mohamed3; Ahmed A. Zaher4; Moustafa E. Moustafa3 | ||||
| 1chemistry Department, Faculty of Science, Benha University, Benha, Egypt | ||||
| 2Polymers and Pigments Department National Research Centre,33 El Bohouth St.(Former El Tahrir St.) Dokki, Giza, 12699, Egypt. | ||||
| 3Chemistry Department, Faculty of Science, Benha University, Benha, Egypt | ||||
| 4Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt and Chemical lab, Egypt army, Nasr city, Egypt. | ||||
| Abstract | ||||
| In this study, Scanning Electron Microscope (SEM) was used to investigate the morphology of untreated and treated cotton fabric, SEM-EDX and mapping were used to prove the presence of phosphate in treated cotton fabric CF. The antimicrobial study of the untreated and treated CF with fire retardancy phosphorous-polymethylmethacrylate (PMMA)/modified montmorillonite (MMT) nanocomposites with diffferent concentrations was done on unicellular fungi (C. albicans), two types of bacteria (L. monocytogenes and S. aureus) as Gram-positive and on another two types of bacteria (Salmonella sp. and E. coli) as Gram-negative. by measuring the inhibition zone diameter. Antimicrobial effect of treated and untreated CF were applied through disc diffusion method. The results showed a good efficiency of treated CF samples with the most of microorganisms than untreated CF. The antimicrobial activity also showed the highest inhibition zone for treated CF with P3 (7 %) of fire retardant phosphorous-PMMA/modified MMT nanocomposites was recorded against L. monocytogenes and Salmonella sp. Also, the molecular docking simulation was investigated to treated CF which showed that the treated CF had high efficiency than pencelien g against positive bacteria and methicillin against negative bacteria. On the other hand, the treated CF showed high efficiency than fluconazole against candida alibicans. | ||||
| Keywords | ||||
| Antimicrobial activity; molecular docking; untreated and treated cotton fabric | ||||
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