The Influence of Dietary Patterns on Immune Function and Inflammation | ||
| Egyptian Journal of Chemistry | ||
| Volume 67, Issue 13, December 2024, Pages 1059-1080 PDF (998.67 K) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2024.325364.10563 | ||
| Authors | ||
| Ahmad Rayan Alfuraydi* 1; Bader Abdulaziz Alazmi1; Abdulaziz Saeed Ali Abushatat2; Ali Hassan Ali Maleh2; Abdul Aziz Saed Al Habshan2; Abdulkarim Hadi Othman Hakami3; Mohammad Duheem Almoutairi4; Tahani Nader Almuzaini4; Ahmed Ali Mufreh Al Essa2; Mohammed Maqbul Mohammed Hazazi5; Mohammad Mamdouh Mohammed Alanazi5; Abeer Khaled Abdulaziz Almutiri6; Modhi Matuq Awwadh Alharthi6; Rasha Awad Atiah Alzahrani6; Abrar Abdulrhman Alharbi7; Shaikha Nasser Muhammad Almutlaq8; Ghadah Sulaiman Alrumaykhan9 | ||
| 1Ministry of Health branch in Al qassim region, Saudi Arabia | ||
| 2Ministry of Health branch in Asir region, Saudi Arabia | ||
| 3Ministry of Health branch in Jazan region, Saudi Arabia | ||
| 4Ministry of Health, Saudi Arabia | ||
| 5Prince Sultan Air Base, Al-Kharj, Saudi Arabia | ||
| 6KING FAISAL MEDICAL COMPLEX (KFMC), Saudi Arabia | ||
| 7AL Yamama Hospital, Saudi Arabia | ||
| 8Riyadh First Health Cluster, Saudi Arabia | ||
| 9King Salman Center for Kidney Diseases, Saudi Arabia. | ||
| Abstract | ||
| Background: Diet significantly impacts immune function and inflammation, with different types of fats, fibers, and micronutrients playing distinct roles. Omega-3 and omega-6 fatty acids, saturated fats, sterols, and dietary fibers all influence immune responses and inflammation, potentially affecting disease risk and management. Aim: This review examines how dietary components such as omega-3 and omega-6 fatty acids, saturated fats, sterols, and fibers affect immune function and inflammation. It aims to elucidate the mechanisms through which these nutrients influence immune responses and their potential implications for disease prevention and management. Methods: We conducted a comprehensive review of the literature, focusing on recent studies that investigate the role of dietary fats, fibers, and micronutrients in immune modulation. Key areas of interest included the impact on inflammatory markers, immune cell function, and disease outcomes. Results: Omega-3 fatty acids exhibit anti-inflammatory properties and may benefit conditions like rheumatoid arthritis, while omega-6 fatty acids are involved in both pro-inflammatory and anti-inflammatory responses. Saturated fats increase inflammation and may exacerbate chronic diseases. Sterols like cholesterol contribute to systemic inflammation and affect immune cell function. Dietary fibers promote gut health and systemic immunity through SCFA production, impacting conditions such as Crohn's disease and metabolic syndrome. Probiotics also modulate immune responses and improve gut health. Conclusion: Dietary components play a crucial role in modulating immune function and inflammation. Omega-3 fatty acids and fibers show potential benefits for reducing inflammation and disease risk, while saturated fats and sterols may contribute to inflammatory responses. Future research should focus on optimizing dietary recommendations to enhance immune health and manage chronic diseases. | ||
| Keywords | ||
| Omega-3 fatty acids; Omega-6 fatty acids; Saturated fats; Sterols; Dietary fibers; Immune function; Inflammation | ||
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