The Role Of MicroRNAs In Psoriasis Vulgaris

MikhaEl, nancy Wadie; Mohamed, Aliaa; Ameen, Seham Gouda; Gab Alla, Samar Omar

doi:10.21608/bjas.2024.328870.1522

	The Role Of MicroRNAs In Psoriasis Vulgaris
Benha Journal of Applied Sciences
Article 12, Volume 9, Issue 10, October 2024, Page 109-113 PDF (375.81 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2024.328870.1522
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Authors
nancy Wadie MikhaEl¹; Aliaa Mohamed²; Seham Gouda Ameen³; Samar Omar Gab Alla ⁴
¹Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University
²Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University
³Assistant Professor of Clinical and Chemical Pathology Faculty of Medicine, Benha University
⁴M.B.B.Ch. Faculty of Medicine, Benha University(2007)
Abstract
Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.
Keywords
STAT3 and NF-κB signaling pathways; are both inhibited; by miR-193b


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