Short-Term Echocardiographic Evaluation by Global Longitudinal Strain in Patients with Heart Failure Treated with Sacubitril/Valsartan | ||||
| Benha Medical Journal | ||||
| Articles in Press, Accepted Manuscript, Available Online from 15 November 2024 PDF (1.05 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bmfj.2024.305147.2134 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Elsayed Abdelkhalek Eldaraky1; Mohamed Abdelshafy Tabl2; Lamiaa Abdelghany Khedr3; Mohammad Mohammad Ibrahim  4; Mahmoud Abdalnaby5
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| 1Professor of Cardiovascular Medicine, Faculty of Medicine, Benha University | ||||
| 2Professor of Cardiovascular Medicine Faculty of Medicine - Benha University | ||||
| 3Professor of Cardiovascular Medicine, Faculty of Medicine Tanta University | ||||
| 4Department of Cardiology Faculty of Medicine - Benha University | ||||
| 5Lecturer of Cardiovascular Medicine Faculty of Medicine – Benha University | ||||
| Abstract | ||||
| Background: Heart failure (HF) is a clinical syndrome characterized by dyspnea, easy fatigability, and fluid retention. This study aimed to assess the effects of ARNI on GLS and myocardial mechanics in patients with HFrEF. Methods: This prospective observational study that included 50 Patients diagnosed with heart failure. All studied cases were subjected to the following: 12-Lead ECG, laboratory investigations [Baseline Serum creatinine (with eGFR calculation using Cockcroft- Gault equation), serum electrolytes, complete blood count, liver function tests and NT-proBNP, Serum creatinine, eGFR calculation and serum electrolytes.], conventional Echo Doppler Study, 2D Speckle tracking Global Longitudinal Strain and medication management. Results: LVEF and peak GLS were significantly improved at 6 months compared to the baseline measurement (P | ||||
| Keywords | ||||
| Short-Term Echocardiographic; Global Longitudinal Strain; Heart Failure; Sacubitril/Valsartan | ||||
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