Diabetic Patients with Gastro-Esophageal Reflux Disease: Comparison Between Two Self-Report Questionnaires.
Taha, A., Elsayed, W., Matar, H., Hassanin, T., Samy, L., Elsayed, N., Abd al aziz, R., Soliman, Z. (2024). Diabetic Patients with Gastro-Esophageal Reflux Disease: Comparison Between Two Self-Report Questionnaires.. EKB Journal Management System, 5(4), 193-207. doi: 10.21608/ejmr.2024.268415.1549
Ahmed El-Sayed Taha; Wael Fathy Elsayed; Hazem Samy Matar; Tarek Ibrahim Hassanin; Lamees Ahmed Samy; Naglaa M. Elsayed; Rasha Ahmed Abd al aziz; Zeinab Abdellatif Soliman. "Diabetic Patients with Gastro-Esophageal Reflux Disease: Comparison Between Two Self-Report Questionnaires.". EKB Journal Management System, 5, 4, 2024, 193-207. doi: 10.21608/ejmr.2024.268415.1549
Taha, A., Elsayed, W., Matar, H., Hassanin, T., Samy, L., Elsayed, N., Abd al aziz, R., Soliman, Z. (2024). 'Diabetic Patients with Gastro-Esophageal Reflux Disease: Comparison Between Two Self-Report Questionnaires.', EKB Journal Management System, 5(4), pp. 193-207. doi: 10.21608/ejmr.2024.268415.1549
Taha, A., Elsayed, W., Matar, H., Hassanin, T., Samy, L., Elsayed, N., Abd al aziz, R., Soliman, Z. Diabetic Patients with Gastro-Esophageal Reflux Disease: Comparison Between Two Self-Report Questionnaires.. EKB Journal Management System, 2024; 5(4): 193-207. doi: 10.21608/ejmr.2024.268415.1549

Diabetic Patients with Gastro-Esophageal Reflux Disease: Comparison Between Two Self-Report Questionnaires.

Egyptian Journal of Medical Research
Volume 5, Issue 4, October 2024, Pages 193-207    PDF (752.77 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2024.268415.1549
Authors
Ahmed El-Sayed Taha1; Wael Fathy Elsayed2; Hazem Samy Matar* 3; Tarek Ibrahim Hassanin4; Lamees Ahmed Samy5; Naglaa M. Elsayed6; Rasha Ahmed Abd al aziz1; Zeinab Abdellatif Soliman1
1Endemic Medicine Department, Faculty of Medicine, Cairo University
2Tropical medicine department - Faculty of Medicine - Beni-Suef University
3Internal Medicine department, Faculty of Medicine, Beni-Suef University, Egypt
4Specialist, endemic heptogastroenterology department, Ahmed Maher Teaching hospital
5Clinical and Chemical Pathology department - Faculty of Medicine - Cairo University
6Internal medicine department Faculty of Medicine, Cairo University
Abstract
Background: Patients with diabetes mellitus (DM) are more likely to have gastroesophageal reflux disease (GERD), and there is a significant association between the two conditions.  A variety of tools, including endoscopy, pH monitoring, and proton pump inhibitor (PPI) test, are available for the diagnosis of GERD. GERD is very prevalent among the majority of people; thus it is highly appealing to apply low-cost, simple methods for identifying high-risk people who might be suffering from it.   Aim: To assess the diagnostic usefulness of the Carlsson-Dent (CD) questionnaire and the frequency scale for detecting the symptoms of the gastroesophageal reflux disease (FSSG) questionnaire as a self-assessment diagnostic instrument in diabetic patients and its relationship with diabetes complications. Patients and methods: This cross-sectional study included 217 adult diabetic patients; 153 females, 64 males who were enrolled in two Endocrinology clinics; the Cairo University hospitals and Beni-Sweif University hospitals from June 2023 to December 2023. All patients were subjected to both CD and FSSG questionnaires (CDQ & FSSGQ respectively). Relevant clinical and laboratory data were gathered such as body mass index (BMI), diabetes control, other comorbidities, added to abdominal ultrasonography. Results: Using the CD questionnaire, GERD was reported in 66% of the study population versus a prevalence of 53% with the FSSGQ. There was a significant agreement between the two questionnaires: of 81.6%, p <0.0001. The presence of hypertension and liver steatosis were significantly associated with GERD diagnosis by the CDQ (P-value 0.03 and 0.004 respectively) and FSSGQ (P-value 0.01 for both). Additionally, NSAID intake, as well as peripheral neuropathy, were associated with GERD using the CDQ (P-value 0.03 and 0.004 respectively). Dyslipidemia was associated with GERD using the FSSGQ (P-value 0.008). Conclusion: A relatively high incidence of GERD symptoms in diabetic patients was observed. There was a significant agreement between the CD and FSSG questionnaires. Hypertension, liver steatosis, dyslipidemia, peripheral neuropathy, and NSAID intake were associated with GERD in diabetics.
Keywords
GERD; DM; FSSG questionnaire; CD questionnaire; HYPERTENSION; DYSLIPIDEMIA; DIABETES; STEATOSIS
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