Study the effect of numbers of transferred embryos on pregnancy and abortion rates in day 3 and day 5 embryo transfer
Said, R., Gaafar, S., Alfeky, B., Sabra, E. (2024). Study the effect of numbers of transferred embryos on pregnancy and abortion rates in day 3 and day 5 embryo transfer. EKB Journal Management System, 20(2), 223-233. doi: 10.21608/ajbs.2024.392984
Radwa A. Said; Sherif S.E. Gaafar; Bahgat A. Alfeky; Ebrahim A. Sabra. "Study the effect of numbers of transferred embryos on pregnancy and abortion rates in day 3 and day 5 embryo transfer". EKB Journal Management System, 20, 2, 2024, 223-233. doi: 10.21608/ajbs.2024.392984
Said, R., Gaafar, S., Alfeky, B., Sabra, E. (2024). 'Study the effect of numbers of transferred embryos on pregnancy and abortion rates in day 3 and day 5 embryo transfer', EKB Journal Management System, 20(2), pp. 223-233. doi: 10.21608/ajbs.2024.392984
Said, R., Gaafar, S., Alfeky, B., Sabra, E. Study the effect of numbers of transferred embryos on pregnancy and abortion rates in day 3 and day 5 embryo transfer. EKB Journal Management System, 2024; 20(2): 223-233. doi: 10.21608/ajbs.2024.392984

Study the effect of numbers of transferred embryos on pregnancy and abortion rates in day 3 and day 5 embryo transfer

African Journal of Biological Sciences
Volume 20, Issue 2, June 2024, Page 223-233  XML PDF (987.31 K)
Document Type: Original Article
DOI: 10.21608/ajbs.2024.392984
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Authors
Radwa A. Saidorcid 1; Sherif S.E. Gaafar2; Bahgat A. Alfekyorcid 3; Ebrahim A. Sabra email orcid 3
1Genetic engineering and Biotechnology Research Institute University of Sadat city, Sadat City, Egypt
2Department of Obstetrics and Gynecology, Faculty of Medicine- Alexandria University.
3Animal Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, University of Sadat City
Abstract
The goal of ART labs over the last ten years was to find embryos with the best chance of implantation. In order to improve selection and increase implantation rates, blastocyst stage transfers on day 5 become more frequent considering that morphology on day 3 embryos may not be a reliable indicator of pregnancy possibility. The current study aimed to assess the clinical outcomes of Day 3 ETs and Day 5 ETs and compare the effect of the number of transferred embryos in clinical pregnancy and early abortion rates performed on D3 and D5. A randomized controlled trial was performed with 200 women under 40 years with primary infertility undergoing ICSI. On day 3 and day 5 ET, participants were divided into two groups of 100 each. After ICSI and controlled ovarian hyperstimulation, ET was carried out under ultrasound monitoring. Clinical pregnancy rates and early abortion rates were among the outcome measures. The current results indicated that there were no significant differences among the two groups regarding sperm parameters, duration of infertility, oocyte retrieval. Day 5 transfers showed the highest clinical pregnancy (71.9%) followed by day 3 (46.9% and 50.0%). Abortion rates were highest on day 3 (50.0%) and lowest on day 5 (12.1%). It was concluded that Day 5 ET yielded the best pregnancy outcomes when compared with Day 3. Further prospective researches are essential to optimize ET numbers and enhance ART outcomes.
Keywords
Blastocyst; cleavage stage; clinical pregnancy; embryo transfer; Early Abortion rate
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