Evaluation the Efficacy of Topically Applied Ciprofloxacin Gel in Treatment of Periodontitis Patients (Clinical, Radiographic and Microbiological Study) | ||||
| Al-Azhar Assiut Dental Journal | ||||
| Volume 7, Issue 2, October 2024, Page 243-254 PDF (1.73 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/aadj.2024.305436.1184 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Asmaa taha Hussein  1; Khalid Seddiek Daifallah2; Ibrahim Hammad Ibrahim3; Abdullah Ibrahim AbdRabbouh 4; Ahmed Mohamed abdelrahman 5
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| 1Department of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology Faculty of Dental Medicine, Al-Azhar University (Assiut branch) | ||||
| 2Professor of Oral Medicine and Periodontology‏ Dean, Faculty of Dental Medicine Al-Azhar University, Assiut Branch | ||||
| 3Department of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology Faculty of Dental Medicine AL-Azhar University (Assiut branch) | ||||
| 4Oral Medicine Periodontology, Oral Diagnosis and Dental Radiology Dean Faculty of Dental Medicine Al-Azhar University (Assiut branch) | ||||
| 5Department of Oral Medicine, Periodontology, and Oral Diagnosis, Faculty of Dentistry, AL-Azhar University, Assiut, Egypt. | ||||
| Abstract | ||||
| Aim: to assess the topical use of ciprofloxacin gel’s microbiological, clinical, and radiographic efficacy in patients with stage I or II, grade A periodontitis as an adjuvant treatment. Subjects and methods: The mean age of the 14 patients was 39±6.55, and they tested positive for Aa. They also had grade A periodontitis, stage I or II. Two patient groups were identified: Patients in Group I received non-surgical periodontal therapy together with an intrapocket application of ciprofloxacin gel, and patients in Group II received non-surgical periodontal therapy exclusively. Results: After one and three months, a statistically significant difference (p-value <0.05) was seen between the baseline. Furthermore, there were statistically significant variations in the gingival index between the two groups at various time intervals from the baseline, as well as a statistically significant variation in the probing depth measurement in each group at various time intervals from the baseline. The clinical attachment level measurements of the two groups were compared at different intervals. There were statistically significant differences between the clinical attachment level measurements of the two groups when compared at different intervals to the baseline. There was no statistically significant difference in the radiographic marginal bone level between the two groups at one, three, or six months from the baseline. Conclusion: Compared to scaling and root planning alone, adjunctive use of ciprofloxacin in-situ gel 1% proved to have a positive impact on both clinical and microbiological parameters of Aa copy number in patients with stage I and II grade A periodontitis. | ||||
| Keywords | ||||
| Scaling; ciprofloxacin; periodontitis; intrapocket application | ||||
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