Inpatient Versus Outpatient Management of Preterm Prelabour Rupture of Membrane. A Prospective Cohort Study
Elmaraghy, A., Kamal, N., Salah El-din, A., Islam, B. (2024). Inpatient Versus Outpatient Management of Preterm Prelabour Rupture of Membrane. A Prospective Cohort Study. EKB Journal Management System, 28(6), 13-24. doi: 10.21608/egyfs.2024.393792
Ahmed Mohammed Elmaraghy; Nermeen Rabea Kamal; Adel Shaï‌k Salah El-din; Bassem Aly Islam. "Inpatient Versus Outpatient Management of Preterm Prelabour Rupture of Membrane. A Prospective Cohort Study". EKB Journal Management System, 28, 6, 2024, 13-24. doi: 10.21608/egyfs.2024.393792
Elmaraghy, A., Kamal, N., Salah El-din, A., Islam, B. (2024). 'Inpatient Versus Outpatient Management of Preterm Prelabour Rupture of Membrane. A Prospective Cohort Study', EKB Journal Management System, 28(6), pp. 13-24. doi: 10.21608/egyfs.2024.393792
Elmaraghy, A., Kamal, N., Salah El-din, A., Islam, B. Inpatient Versus Outpatient Management of Preterm Prelabour Rupture of Membrane. A Prospective Cohort Study. EKB Journal Management System, 2024; 28(6): 13-24. doi: 10.21608/egyfs.2024.393792

Inpatient Versus Outpatient Management of Preterm Prelabour Rupture of Membrane. A Prospective Cohort Study

The Egyptian Journal of Fertility and Sterility
Volume 28, Issue 6 - Serial Number 11106352, November 2024, Page 13-24  XML PDF (401.1 K)
Document Type: Original Article
DOI: 10.21608/egyfs.2024.393792
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Authors
Ahmed Mohammed Elmaraghy email orcid 1; Nermeen Rabea Kamal2; Adel Shaï‌k Salah El-dinorcid 3; Bassem Aly Islamorcid 3
1Department of Obstetrics & Gynecology - Faculty of Medicine – Ain Shams University –Cairo – Egypt
2Department of Obstetrics & Gynecology – Bolak Eldakror General Hospital – Ministry of Health – Cairo - Egypt
3Department of Obstetrics & Gynecology – Faculty of Medicine – Ain Shams University –Cairo – Egypt
Abstract
Objective: To assess the effectiveness and safety of the outpatient management approach for patients with preterm prelabour rupture of membrane regarding the latency period, incidence of chorioamnionitis, and neonatal outcomes.   
Patients and Methods: This prospective cohort study included 63 Patients with confirmed diagnosis of PPROM. All included patients were admitted to the inpatient ward for 48 hours where they received IV antibiotics and corticosteroids for fetal lung maturation then, 31 patients were managed as outpatient and 32 patients were managed as inpatient. The primary outcome was the latency period and gestational age at birth while the incidence of chorioamnionitis, and neonatal outcomes in terms of neonatal weight, neonatal intensive care (NICU) admission, and neonatal sepsis were secondary measures of outcome.    
Results: The latency period (days) was significantly longer (29.4±15.8 vs 17.7±11.9, p 0.002) and the gestational age (weeks) at birth was significantly higher (35.0±1.8 vs 33.6±1.9, p 0.004) among the outpatient arm. There was no significant difference between the two arms regarding the incidence of chorioamnionitis, neonatal weight, NICU admission and neonatal sepsis.
Conclusion: Outpatient management of patients with PPROM is safe approach which can be adopted particularly in low risk patients. 

Keywords
Key words: Preterm prelabor rupture of membrane; outpatient management; latency period; chorioamnionitis; neonatal outcomes
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