The Role of Central Venous Oxygen Saturation as A Predictor of Outcome after Valve Replacement
Fathi sherif, A., Saied Abd El-azeem, E., Mofreh Aglan, B., Shafik Abdel Hamid, E., Mohamed Hassan Anan, T., Afify Saad, D. (2025). The Role of Central Venous Oxygen Saturation as A Predictor of Outcome after Valve Replacement. EKB Journal Management System, 42(4), 391-402. doi: 10.21608/bmfj.2024.325232.2216
Abdelhamid Fathi sherif; Ehab Saied Abd El-azeem; Basem Mofreh Aglan; Eman Shafik Abdel Hamid; Tarek Mohamed Hassan Anan; Dina Afify Saad. "The Role of Central Venous Oxygen Saturation as A Predictor of Outcome after Valve Replacement". EKB Journal Management System, 42, 4, 2025, 391-402. doi: 10.21608/bmfj.2024.325232.2216
Fathi sherif, A., Saied Abd El-azeem, E., Mofreh Aglan, B., Shafik Abdel Hamid, E., Mohamed Hassan Anan, T., Afify Saad, D. (2025). 'The Role of Central Venous Oxygen Saturation as A Predictor of Outcome after Valve Replacement', EKB Journal Management System, 42(4), pp. 391-402. doi: 10.21608/bmfj.2024.325232.2216
Fathi sherif, A., Saied Abd El-azeem, E., Mofreh Aglan, B., Shafik Abdel Hamid, E., Mohamed Hassan Anan, T., Afify Saad, D. The Role of Central Venous Oxygen Saturation as A Predictor of Outcome after Valve Replacement. EKB Journal Management System, 2025; 42(4): 391-402. doi: 10.21608/bmfj.2024.325232.2216

The Role of Central Venous Oxygen Saturation as A Predictor of Outcome after Valve Replacement

Benha Medical Journal
Article 6, Volume 42, Issue 4, April 2025, Page 391-402  XML PDF (783.68 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2024.325232.2216
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Authors
Abdelhamid Fathi sherif1; Ehab Saied Abd El-azeem2; Basem Mofreh Aglan3; Eman Shafik Abdel Hamid4; Tarek Mohamed Hassan Anan email 5; Dina Afify Saad6
1Lecutrer of Cardiothoracic surgery, Banha University, Egypt
2Professor of Anesthesia and Critical Care, Faculty of Medicine, Benha University, Egypt
3Assistant Professor of Cardiothoracic Surgery, Faculty of Medicine, Benha University, Egypt
4Lecturer of Critical Care Medicine, Faculty of Medicine, Benha University, Egypt
5M.B.B.Ch, Faculty of Medicine, Benha University, Benha, Egypt
6Lecturer of Cardiothoracic Surgery, Faculty of Medicine, Benha University, Egypt
Abstract
Background: The nonregenerative valve replacements have been developed to ensure long term functionality upon implantation without possibility of integration, remodeling, or growth. This study aimed to assess the role of central venous oxygen saturation (ScvO2) as a predictor of outcome after valve replacement. Methods: This prospective cross-sectional study was conducted on 50 patients who underwent valve replacement. All studied cases underwent history taking and demographic data collection, hemodynamic parameters and routine investigations. Results: There was a statistically significant negative correlation between ScvO2 level on induction and 48h. postoperative with MV duration, while its level on induction only was negatively correlated with ICU length of stay. There was high sensitivity of ScvO2 level in prediction of unfavorable outcome on induction of anesthesia (84.6%) and 48 hours postoperative (74.4%) at cut off < 75.5 & 73.5 respectively, with significant high-test accuracy of 80% and 70% respectively. Conclusion: ScvO2 is a valuable predictor of outcomes in patients undergoing valve replacement surgery. Significant changes in ScvO2 levels over time were strongly associated with ICU length of stay and duration of mechanical ventilation, with lower ScvO2 levels on induction and at 48 hours postoperatively correlating with worse outcomes, such as longer ICU stays and prolonged mechanical ventilation. These findings suggest that monitoring ScvO2 could aid in early identification of patients at risk of complications and unfavorable outcomes, potentially guiding more targeted postoperative care.
Keywords
Central venous Oxygen saturation; Predictor; Outcome; Valve Replacement
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