Biochemical Pathophysiology of Hypertension: Nursing Interventions in Blood Pressure Regulation and Treatment | ||||
Egyptian Journal of Chemistry | ||||
Volume 67, Issue 13, December 2024, Page 1387-1398 PDF (377.09 K) | ||||
Document Type: Review Articles | ||||
DOI: 10.21608/ejchem.2024.336261.10800 | ||||
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Authors | ||||
Khadij Barri Ahmad Qaissi1; Maram Abdullah Almutiri2; Mariam Kassb Alrowili3; Tasneem Saeed Almahroos4; Amnah Farhan Albaker4; Salha Jubran Yahya Aqeeli4; Nadiah Munahi Al-Mutairi4; Ashwaq Ali Almohsen5; Tala Saeed Almutiari4; Bashaeraa Attalah Bakyt Alanazy6; Awatif Muteb Rajah Almuteri7; Mariam Mohammed Almutiri7; Abdullah Mashlah Aldosari8; Fatimah Hassan Al Abbas9; Afaf Ahmad Kriri10 | ||||
1Primary Health Care Center, Ministry of Health, Saudi Arabia | ||||
2Qassim Gathering, Ministry of Health, Saudi Arabia | ||||
3Hafr Al-Batin Health Cluster, Ministry of Health, Saudi Arabia | ||||
4Second Health Cluster, Ministry of Health, Saudi Arabia | ||||
5Riyadh Health Cluster II, Ministry of Health, Saudi Arabia | ||||
6King Khalid Hospital, Ministry of Health, Saudi Arabia | ||||
7Cluster2_Riyadh, Riyadh - Airport Primary Health Care Center, Ministry of Health, Saudi Arabia | ||||
8Wadi Al Dawasir Hospital, Ministry of Health, Saudi Arabia | ||||
9First Health Cluster Al-Adamah Health Care Center, Ministry of Health, Saudi Arabia | ||||
10The first health cluster - King Khalid Al-Kharj Hospital - Al-Kattar District Health Center in Al-Kharj, Ministry of Health, Saudi Arabia | ||||
Abstract | ||||
Background: Hypertension is a major public health issue worldwide, with high prevalence rates but low levels of awareness, treatment, and control. Despite its impact on cardiovascular health and its association with numerous risk factors, the management of hypertension remains suboptimal, particularly in low-resource settings. Emerging risk factors such as sugar intake, air and noise pollution, and low birth weight add complexity to the condition's pathophysiology. Effective hypertension management requires accurate diagnosis, improved treatment adherence, and tailored interventions across multiple healthcare sectors. Aim: This article aims to examine the biochemical pathophysiology of hypertension and explore the role of nursing interventions in blood pressure regulation and treatment. It will also highlight the emerging risk factors, current challenges in hypertension management, and the importance of biomarkers in improving diagnosis and treatment. Methods: A review of current literature on hypertension management was conducted, focusing on risk factors, challenges in diagnosis and control, and emerging strategies to improve treatment adherence. Relevant clinical guidelines and research on biomarkers were also analyzed to understand their role in hypertension care. Results: The article identifies several emerging hypertension risk factors such as sugar intake, air pollution, and noise, which complicate treatment strategies. Challenges in hypertension management include inadequate health services, difficulty in diagnosing hypertension, and poor treatment adherence. Biomarkers, including genetic, molecular, and functional biomarkers, hold significant promise for early diagnosis, risk stratification, and personalized treatment strategies. The article also emphasizes the roles of patients, physicians, health authorities, nurses, and pharmacists in improving hypertension management. Conclusion: The future of hypertension management lies in enhancing awareness, improving diagnostic accuracy, and integrating new biomarkers into clinical practice. National programs, targeted interventions, and financial coverage expansion are crucial to improving blood pressure control, particularly in resource-limited settings. Nurses, alongside physicians and other healthcare providers, have an essential role in patient education and adherence strategies. Effective integration of biomarkers into routine care could revolutionize hypertension management and lead to better long-term outcomes | ||||
Keywords | ||||
Hypertension biomarkers; blood pressure control; genetic biomarkers; emerging risk factors; healthcare challenges | ||||
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