Drug-coated balloon versus provisional percutaneous transluminal coronary angioplasty to side branch in bifurcation lesions | ||||
| Benha Medical Journal | ||||
| Article 739, Volume 42, Issue 2, February 2025, Page 213-224 PDF (963.17 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bmfj.2024.302670.2119 | ||||
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| Authors | ||||
Mohamed Sadawi  1; Tarek Helmy Abo EL Azm2; Mohamed Abd EL Shafy Tabl2; Mohamed Selim Mohamed3; Sherien Ibrahim Farag4
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| 1Cardiology, Faculty of Medicine, Benha University, Egypt | ||||
| 2Professor of Cardiology, Faculty of Medicine, Benha University, Egypt | ||||
| 3Consultant of cardiology, National Heart Institute, Egypt | ||||
| 4Assistant Professor of Cardiology, Faculty of Medicine, Benha University, Egypt | ||||
| Abstract | ||||
| Background: Interventions involving coronary artery bifurcation lesions are technically demanding and have been historically linked with lower procedural success rates and poorer clinical outcomes compared to non-bifurcation lesions, necessitating specialized preparation and distinct expertise. This study aimed to contrast the application of drug-coated balloons with that of conventional balloons in the provisional stenting of coronary artery bifurcation lesions. Methods: The study is an interventional clinical trial . sixty participants who fulfilled the inclusion criteria were recruited into our study and divided into two categories: Group A: Patients who underwent provisional stenting using the traditional method with plain balloon angioplasty. Group B: Patients who underwent provisional stenting using a drug-coated balloon. Immediate patient outcomes were evaluated, and a clinical follow-up was conducted after six months to monitor for major adverse cardiac events. Results: Our study indicates that Drug-coated balloons (DCBs) have surfaced as a compelling therapeutic strategy in managing coronary bifurcation lesions. A substantial difference was noted between group A and group B to MACE after 6 months. The incidence of MACE was 28.6% (8 out of 30 patients) in group A, compared to 3.3% (1 patient) in group B, with a p-value of 0.02. However, no significant difference was observed between the two groups regarding in-hospital MACE in this study. The secondary endpoint of the study was defined as lesion success, and procedure success. Conclusion: our study highlighted the promising results of drug-coated balloons and their potential utilization in managing coronary artery bifurcation lesions. | ||||
| Keywords | ||||
| Drug-coated balloons; coronary bifurcation lesions; PCI | ||||
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