SYSTEMATIC REVIEW OF THE EFFECTS OF ACANTHAMOEBA POLYPHAGA MIMIVIRUS (APMV) INFECTION ON VIRULENCE OF ACANTHAMOEBA POLYPHAGA (AP) | ||
| Journal of the Egyptian Society of Parasitology | ||
| Article 4, Volume 54, Issue 3, December 2024, Pages 369-380 PDF (7.32 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jesp.2024.397251 | ||
| Author | ||
| YASIR MOHAMMED A. ALQURASHI | ||
| Department of Medical Laboratory, College of Applied Medical Sciences, Taibah University, Yanbu, 46422, Saudi Arabia | ||
| Abstract | ||
| The interactions between Acanthamoeba polyphagan (AP) and Acanthamoeba polyphaga mi- mivirus (APMV) play a crucial role in their virulence and adaptability. This systematic review synthesises findings from 41 studies published between 2003 and 2024 to evaluate how APMV infection impacts these organisms. The review highlights key genetic and molecular changes, in cluding alterations in gene expression, phagocytosis, and encystment, alongside the influence of environmental factors. APMV infection significantly affects virulence, driven by complex sym biotic relationships. The review gave a clearer understanding of AP & APMV interactions, with implications for microbial ecology and disease management. | ||
| Keywords | ||
| Acanthamoeba polyphaga mimivirus; A. polyphaga; Virulence; Review | ||
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