IN VITRO STUDY ON THE ANTIPARASITIC EFFECT OF OMEPRAZOLE ON CRYPTOSPORIDIUM PARVUM

ATALLAH, MAI A.; EL-KOWRANY, SAMY I.; AFIFI, OMAYMA K.; ELKALINY, HEBA H.; YOUNIS, SALWA S.; GAMEA, GHADA A.

doi:10.21608/jesp.2024.397261

	IN VITRO STUDY ON THE ANTIPARASITIC EFFECT OF OMEPRAZOLE ON CRYPTOSPORIDIUM PARVUM
Journal of the Egyptian Society of Parasitology
Article 14, Volume 54, Issue 3, December 2024, Page 453-458 PDF (3.43 MB)
Document Type: Original Article
DOI: 10.21608/jesp.2024.397261
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Authors
MAI A. ATALLAH¹; SAMY I. EL-KOWRANY¹; OMAYMA K. AFIFI²; HEBA H. ELKALINY³; SALWA S. YOUNIS⁴; GHADA A. GAMEA¹
¹Department of Medical Parasitology, Faculty of Medi cine, Tanta University, Egypt
²Department of Histology, Faculty of Medi cine, Tanta University, Egypt
³Department of Histology and Anatomy, Mutah University, Mutah, Jordan
⁴Department of Medical Parasitology Faculty of Medicine, Alexandria University, Egypt
Abstract
Cryptosporidiosis is an important zoonotic diarrheal disease of worldwide distribution in man animals as well water canals, causing about one million deaths annually. This study investigated the anti-parasitic and anti-inflammatory effects of omeprazole versus nitazoxanide and as a combined therapy to treat Cryptosporidium parvum infection in tissue culture. Histopathological and SEM examinations on infected tissue cultures evaluated treatment. The results showed marked treated and inflammation improvement with omeprazole over nita zoxanide combined treatment as indicated by histopathological and SEM studies.
Keywords
Cryptosporidiosis; Culture; Omeprazole; Nitazoxanide Histopathology; SEM


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