LARVICIDAL EFFICACY OF HYPTIS PECTINATA LEAF EXTRACTS AGAINST AEDES AEGYPTI 4TH INSTAR LARVAE IN NIGERIA | ||||
Journal of the Egyptian Society of Parasitology | ||||
Volume 54, Issue 3, December 2024, Page 491-498 PDF (4.97 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jesp.2024.397265 | ||||
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Authors | ||||
BLESSING C. NWASO1; ADENIRAN J. IKUESAN1; ESE S. IZEKOR1; EZE E. AJAEGBU* 2; ABDULRASHEED M. BELLO1; IJEOMA O. OKOLO1; NNYENEIME U. BASSEY1; UKACH-UKWU C. EZEH1; ADAOBI J. DIEKE1; CHINENYE A. NWOBODO1; FLORENCE O. NDUKA1 | ||||
1Department of Applied Sciences, Federal College of Dental Technology and Therapy, Trans-Ekulu Enugu State, Nigeria | ||||
2Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, David Umahi Federal University of Health Sciences, Uburu Ebonyi State, Nigeria | ||||
Abstract | ||||
Yellow fever, Dengue fever, Chikungunya, and Zika virus are risky Aedes aegypti-borne infectious diseases among natives and travelers who travel to endemic countries globally. A total of 10g of each rigorously weighed dried leaf of Hyptis pectinata and four extracts (hexane, DCM, acetone, ðanol) at concentrations of 125, 250, 500, & 1000ppm were evaluated for larvicidal activities against Ae. ae gypti 4th instar larvae. LC50 mortality increased to 100%, 20%, 60%, & 60% at 500ppm of hexane, DCM, acetone, and eth anol extract (171, 203, 419 & 449 ppm, respectively), after 24 hours laboratory exposure. This inex pensive medicinal plant reduced mosquitoes and thus can control their infectious parasitic and viral diseases. | ||||
Keywords | ||||
Aedes aegypti; Hyptis pectinata; extracts; larvicidal; control; mortality | ||||
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