Effects Of CANDEREL® and The Ameliorative Role of Stem Cell Enhancer on Some Physiological Parameters in Male Albino Rats | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 13, Volume 76, Issue 3, July 2019, Pages 3702-3708 PDF (501.29 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2019.39915 | ||
| Authors | ||
| Eman G.E. Helal* 1; Mohamed A. Abdelaziz2; Mariam S. El-Gamal1 | ||
| 1Department of Zoology, Faculty of Science (Girls), Al-Azhar University | ||
| 2Medical Physiology, Faculty of Medicine, Al-Azhar University | ||
| Abstract | ||
| Background: CANDEREL® is non-nutritive artificial sweetener, which is mainly composed of aspartame and acesulfame potassium. Materials and Methods: thirty male albino rats weighing from 100 to 120 gm. The period of the experiment was 30 days. The animals were divided into three groups; group 1: control, group 2: rats received CANDEREL® (1 tablet/25kg b.w./day) and group 3: rats received CANDEREL® (1 tablet/25kg b.w./day) + SCE (9 mg/kg b.w./day). The following parameters were measured: serum glucose, ASAT, ALAT, serum creatinine, serum urea, protein and lipid profiles and hormonal levels (insulin, testosterone, serum T3 and serum T4). Results: there were many disturbances that occurred in the previous parameters, and SCE ameliorated most of these hazardous effects. Conclusion: artificial sweeteners are not safe in use; their disadvantages are more than their advantages. So, we recommended replacing non-nutritive sweeteners with nutritive ones to be away from any hazardous effects that may result from the use of artificial sweeteners. Also, SCE made a great job in fighting the impairments that occur during the experiment. | ||
| Keywords | ||
| CANDEREL®; Aspartame; acesulfame potassium; Stem Cell Enhancer; ASAT; ALAT; T3; T4; testosterone; Insulin | ||
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