THERAPEUTIC EFFECT OF SPIRULINA VERSUS PLATELET-RICH PLASMA ON INDOMETHACIN–INDUCEDGASTRIC ULCER IN BLACK MICE | ||
| ALEXMED ePosters | ||
| Article 1, Volume 6, Issue 4, September 2024, Pages 95-96 | ||
| Document Type: Preliminary preprint short reports of original research | ||
| DOI: 10.21608/alexpo.2024.346630.2045 | ||
| Authors | ||
| Maha Diaa1; Rasha Rabea Abdelhameed1; Sally Mahmoud Mohamed Hussein Mahmoud Mohamed Hussein1; Neama Mohamed Abdelfattah Elbanawany2; Aya Hany Refaat Badawy Elshennawy* 1 | ||
| 1Department of Human Anatomy and Embryology, Faculty of Medicine, Alexandria University | ||
| 2Department of Histology and Cell Biology, Faculty of Medicine, Alexandria University | ||
| Abstract | ||
| Gastric ulcers are considered among the most important and prevalent gastrointestinal disorders nowadays. Gastric ulcer is as a lesion in the gastric mucosa that may extend to reach the muscularis mucosa.one of the most common inducing factors is non-steroidal anti-inflammatory drugs (NSAIDs). Indomethacin is a typical NSAID known for itsanti-inflammatory, analgesic, and antipyretic properties but it has a higherulcerogenic potential on the stomach compared to other NSAIDs. The majority of gastric ulcer treatments currently available are expensive, having high risk of ulcer recurrence and side effects. That's why we are continuously looking for natural alternatives that are safer, less expensive and more effective against gastric ulcers.PRP is a blood product rich in growth factors that enhances tissue regeneration and repair. Spirulina is a natural dried alga having a lot of vitamins, proteins and antioxidants which promotes healing in many organs. AIM OF THE WORK The aim of this work was to compare the potential therapeutic effect of Spirulina and the platelet-rich-plasma (PRP) on indomethacin–induced gastric ulcer in adult male black mice. | ||
| Keywords | ||
| Gastric ulcers; SPIRULINA; PLATELET-RICH PLASMA | ||
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