EVALUATION OF ESTROGEN AND PROGESTERONE RECEPTORS STATUS IN ENDOMETRIOID & NON-ENDOMETRIOID ENDOMETRIAL CANCER. | ||
| ALEXMED ePosters | ||
| Article 1, Volume 6, Issue 4, September 2024, Pages 100-101 | ||
| Document Type: Preliminary preprint short reports of original research | ||
| DOI: 10.21608/alexpo.2024.348555.2052 | ||
| Authors | ||
| Hassan Mansour Hegab1; Hossam Hassan Elsokary1; Ahmed abdelazim2; Eman Sheta Ali3; Taghreed Ahmed Shaker Mohamed El Morsy* 2 | ||
| 1Obstetrics and gynecology faculty of medicine | ||
| 2Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University | ||
| 3Department of Pathology, Alexandria Faculty of Medicine, Alexandria University | ||
| Abstract | ||
| A change in the estrogen and progesterone balance toward a more hyperestrogenic state raises the risk of EC. EC is classified as either estrogen-dependent (endometrioid carcinoma; EEC) or non-estrogen-dependent (non-endometrioid carcinoma; non-EEC). EECs are more prevalent, representing 80% of EC patients. Non-EECs are rarer. In the literature, the best-established predictive indicators for EC are the estrogen receptor (ER) and the progesterone receptor (PR). Most of ECs are ER and PR-positive. It was hypothesized that EEC and non-EEC would have distinct ER or PR positivities. Other research, however, proposed that the subtypes of ECs share a number of risk variables and that the non-EEC would not be entirely estrogen-independent. Herein, this comparative study intended to detect the presence of ER or PR in endometrium in both endometrioid and non-endometrioid EC. AIM OF THE WORK: The aim of this study was to detect the presence of ER or PR in endometrium in both endometrioid and non-endometrioid endometrial cancer. | ||
| Keywords | ||
| EEC; EC; Non-EEC | ||
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