Water Soluble Bone Hemostatic Agent, Was It Effective In Reducing Post-Sternotomy Wound Infection? | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 12, Volume 98, Issue 1, January 2025, Page 80-83 PDF (333.35 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2025.401102 | ||||
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| Abstract | ||||
| Background: The widely utilized Bone Wax (BW) in sealing sternal wound edges is a well-known risk factor for delayed healing and post-sternotomy wound infection, and despite the variety of bone sealants available, we have little data on their effectiveness and safety in sternal wound hemostasis. Objective: This study aimed to assess effectiveness and safety of water-soluble bone wax (WSW; Ostene® or Tableau Wax®) hemostatic agents as alternative for the ordinary bone wax (BW). Methods: This study included 323 patients who underwent elective cardiac surgeries via median sternotomy at Kasr-Alainy, Fayoum, and Beniseuf University Hospitals through the period from January 2020 to September 2024. They were divided into two groups: Group A (the control or BW group), which had 165 patients, and group B (the WSW group), which had 158 patients. Postoperative data regarding clinical and radiological signs of wound healing and infection were gathered and analyzed. Results: The WSW group had a significantly decreased incidence of superficial (12 vs. 25) and deep sternal wound infection (DSWI; 2 vs. 9), as well as a shorter hospital stay (5.8 ± 3.4 vs. 6.7 ± 4.5 days). A trimonthly radiologic follow-up showed that the BW group had considerably worse sternal bone repair than the WSW group (p < 0.0001). Conclusion: Whenever necessary, topical sternal edge hemostasis could be securely and effectively done with water-soluble bone sealants with superior surgical outcomes. | ||||
| Keywords | ||||
| Cardiac surgery; Bone hemostatic agent; Wound infection; Sternal wound healing | ||||
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