Biochemical effect of locally delivered tea tree oil gel as an adjunct to non-surgical periodontal therapy: A Randomized Controlled Trial | ||
| Egyptian Dental Journal | ||
| Volume 71, Issue 1 - Serial Number 3, January 2025, Pages 411-418 PDF (442.39 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2024.342281.3293 | ||
| Authors | ||
| Hadeel Gamal Almalahy1; Rawan Ayman Ebrahim* 2; hala A. Abuel Ela3 | ||
| 1Lecturer of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Ain Shams University, Cairo, Egypt | ||
| 2Professor at Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. | ||
| 3Assistant Lecturer at Department of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Misr International University, Cairo, Egypt. | ||
| Abstract | ||
| Objective: This study's main objective was to assess the therapeutic benefits of using Tea Tree Oil (TTO) gel intrapocket as a supplement to non-surgical periodontal therapy. Methods and materials: A three-month, double-blind, randomized, controlled biochemical trial including 22 individuals with Stage III Grade B periodontitis was carried out. Randomly selected patients were allocated to two treatment groups: group I received NSPT plus locally applied TTO gel at the site of the deepest probing pocket depths (PPD); group II received NSPT alone. At 0 and 90 days after treatment, GCF samples were collected for biochemical analysis for Tumor Necrosis Factor Alpha (TNF -α), as well as Oral Health Impact Profile (OHIP-14) questionnaire. Results: The outcomes demonstrated that, in comparison to the baseline, both groups' metrics had improved. The test group showed a much greater decrease in TNF-α level. Patients in both groups expressed the same degree of satisfaction. Conclusion: Tea tree oil gel may be more effective at reducing periodontal inflammation when used in conjunction with non-surgical periodontal therapy. Keywords: Nonsurgical periodontal treatment, Periodontitis, Tea tree oil, Local Drug Delivery. | ||
| Keywords | ||
| Nonsurgical periodontal treatment; Periodontitis; Tea tree oil; Local Drug Delivery | ||
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