The Ability of the Albumin-Bilirubin Grade to Predict the Short-Term Outcomes & Complications Following Hepatic Resection | ||
| The Egyptian Journal of Surgery | ||
| Volume 44, Issue 1, January 2025, Pages 91-97 PDF (339.45 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejsur.2024.306158.1130 | ||
| Authors | ||
| Essam M. Salah; Ibrahim K. Marwan; Mohammad T. Badawy; Amr I. El Disoki* ; Ahmed N. Sallam | ||
| Department of Hepatobiliary and Pancreatic Surgery, National Liver Institute, Menoufia University, Menofia, Egypt. | ||
| Abstract | ||
| Background: Hepatocellular carcinoma (HCC) is the 2nd leading cause of cancer-associated mortality globally. Aim: To evaluate the albumin-bilirubin (ALBI) grade as a prognostic tool in assessing cases undergoing hepatectomy for early post-operative complications in comparison to other scores/grades. Patients and methods: This prospective research has been performed on 42 cases with HCC that were subjected to elective hepatic resection at the National Liver Institute at Menoufia University. Results: The ALBI score had 66.7% sensitivity and 93.9% specificity at a threshold value of > 2 with AUC = 0.825 and was highly significant (P = 0.001). The CHILD score had a 55.6% sensitivity and 75.8% specificity at a threshold value of > 5% with AUC = 0.640 and was non-significant (p = 0.136). The model for end-stage liver disease (MELD) score at a threshold value 8.35 had 100% sensitivity and 21.2% specificity, with AUC = 0.519, and was non-significant (P = 0.868). Conclusion: The albumin-bilirubin score demonstrated greater predictive value for liver cell failure compared with the Child-Pugh score as well as the model for end-stage liver disease score. The ALBI score, as well as bilirubin can be used as independent predictors for liver cell failure and bile leak post-hepatic resection in HCC patients. | ||
| Keywords | ||
| HCC; ALBI score; hepatic resection; MELD score | ||
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