The Role of Perioperative Vitamin D Measurement after Total Thyroidectomy as a Predictor of Hypocalcemia | ||||
| The Egyptian Journal of Surgery | ||||
| Volume 44, Issue 1, January 2025, Page 207-212 PDF (309.19 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejsur.2024.311227.1157 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed Saeed Hassan Saqr  ; Moataz Mohamed Abo-elazm; Beshoy Safwat Adib; Mohamed Saied El-marzouki; Mai Mohamed Alsadat Ahmed
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| Department of General Surgery, Faculty of Medicine, Cairo University, Egypt. | ||||
| Abstract | ||||
| Background: Temporary hypocalcemia, a common occurrence after total thyroidectomy, affects up to 35% of patients, presenting mild to severe symptoms such as paresthesia, tingling, cramps, tetany, and convulsion. Aim: To discuss the relation between vitamin D and postoperative hypocalcemia in patients undergoing total thyroidectomy and to determine the optimal vitamin D threshold level to reduce hypocalcemia risk, enabling judicious and goal-directed vitamin D replacement. Patients and methods: This prospective study was conducted on 200 patients with hypocalcaemia underwent total thyroidectomy in kasr el-ainy university hospitals, Faculty of Medicine, Cairo University from 2023 Results: Age, female patients, ALP, and hospital stay were significantly higher in patients who developed postoperative Ca ≤ 8 mg/dl than those who developed postoperative Ca > 8 mg/dl (P value <0.001). Preoperative and postoperative Ca and preoperative 25-OHD were significantly lower in patients who developed postoperative Ca ≤ 8 mg/dl than those who developed postoperative Ca > 8 mg/dl (P value <0.001). Albumin and creatinine were insignificantly different between patients who developed postoperative Ca ≤ 8 mg/dl and those who developed postoperative Ca > 8 mg/dl. Conclusion: Patients who developed postoperative hypocalcemia had significantly lower preoperative 25-OHD levels compared to those who did not develop hypocalcemia. Additionally, older age and female gender were identified as risk factors for postoperative hypocalcemia. The study also demonstrated a positive correlation between postoperative calcium levels and preoperative 25-OHD levels, suggesting that adequate vitamin D status may play a protective role against postoperative hypocalcemia. | ||||
| Keywords | ||||
| Vitamin D; hypocalcemia; total thyroidectomy | ||||
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