Prevalence and risk factors of human Bocavirus infection among pediatric patients with community-acquired pneumonia | ||
| Microbes and Infectious Diseases | ||
| Volume 6, Issue 2, May 2025, Pages 551-559 PDF (707.5 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mid.2025.341941.2382 | ||
| Authors | ||
| Reham H A Yousef1, 2; Eman Hany Elsebaie3; Heba Ahmed ElAwady4; Norhan Osama El-Helw5; Basma Ahmed Elawady* 6 | ||
| 1Department of Microbiology Immunology, Arabian Gulf University, Bahrain | ||
| 2Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University | ||
| 3Public Health and Community Medicine Department, Faculty of Medicine, Cairo University, Egypt | ||
| 4Department of Pediatrics, Faculty of Medicine, Fayoum University, Egypt | ||
| 5Medical Microbiology and Immunology Department, Faculty of dentistry, Alryada University for Science and Technology, Egypt | ||
| 6Medical Microbiology and Immunology Department, Faculty of Medicine, Cairo University, Egypt | ||
| Abstract | ||
| Background: Human bocavirus (HBoV) in particular HBoV-1 is a parvovirus commonly found in the respiratory tract of young children. Infection with HBoV-1 can cause cough, sore throat, nausea and headache that can last for 1-2 weeks. Our objective was to detect the presence of HBoV-1 in nasopharyngeal aspirate of children with community-acquired pneumonia (CAP) and to identify the relevant risk factors. Methods: Ninety nasopharyngeal aspirates from patients (aged 0-5 years) which were diagnosed clinically and radiologically with CAP admitted to the emergency department of two tertiary care hospitals from January to April. All specimens were subjected to routine culture technique as well as real-time RCR. Results: Out of 90 upper respiratory samples, HBoV-1 infection was detected in 3 cases (3.3%) with upper coryza and tachypnea. Pseudomonas and Klebsiella species were also isolated from sputum samples. Conclusion: HBoV-1 was one of the causal factors of CAP, even as a sole agent or with other co-infections. | ||
| Keywords | ||
| community-acquired pneumonia; human bocavirus; HBoV-1; co-infections; nasopharngeal aspirate | ||
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