Letrozole a Novel Treatment for Undisturbed Ectopic Pregnancy | ||
| SVU-International Journal of Medical Sciences | ||
| Article 89, Volume 7, Issue 2, July 2024, Pages 1031-1037 PDF (332.47 K) | ||
| Document Type: Original research articles | ||
| DOI: 10.21608/svuijm.2023.189322.1504 | ||
| Authors | ||
| Abd EL-Naser Abd EL-Gaber Ali; Mostafa Khodry; Moaz Hamada Mohamed* | ||
| Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, Egypt | ||
| Abstract | ||
| Background: The fallopian tube is where ectopic pregnancies most frequently occur. Methotrexate or minimally invasive surgery can successfully treat the majority of early-detected tubal ectopic pregnancy cases. Objectives: This study's objective is to evaluate letrozole as a potential new treatment for ectopic pregnancy. Patients and methods: The Obstetrics and Gynecology Department of Qena University Hospital carried out this cohort study. The study included 40 cases with non-disturbed ectopic tubal pregnancy. They were divided into two groups; group took Letrozole (20 cases), and group took methotrexate (20 cases). The duration of the study ranged from 6- 12months. Results: as regard success of treatment was achieved in 85% of letrozole cases versus 80% in methotrexate cases with insignificant differences. Maternal morbidity was insignificant between two groups as in letrozole group 2 cases transferred to surgery and 1 case shifted to methotrexate, in methotrexate 4 cases transferred to surgery. Conclusion: Success rates for both treatment arms of letrozole and methotrexate were 86%. Even though the difference was statistically significant, women treated with letrozole rather than methotrexate tended to experience a faster decline in B-Human Chorionic Gonadotropin levels. | ||
| Keywords | ||
| Letrozole; Undisturbed ectopic pregnancy; beta HCG; Medical treatment; Methotrexate | ||
|
Statistics Article View: 126 PDF Download: 76 |
||
