Comparative Analysis of Full Arc and Partial Arc VMAT Techniques for Prostate Cancer SBRT: Evalu-ating Plan Quality and Treatment Delivery Parameters | ||||
| Global Journal of Scientific Research | ||||
| Volume 2, Issue 1, January 2025, Page 10-22 PDF (6.28 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/gjsr.2025.404906 | ||||
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| Abstract | ||||
| This study presents a comprehensive investigation of the radiotherapy plan quality and treatment delivery parameters of two distinct volumetric-modulated arc therapy (VMAT) approaches, full arc and partial arc, for prostate cancer stereotactic body radiation therapy (SBRT). Fifteen retrospective prostate cancer patients were included in this study. Following the Radiation Therapy Oncology Group (RTOG) 0938 protocol guidelines, thirty treatment plans were generated utilizing two full arcs and two partial arcs VMAT. Dosimetric parameters were evaluated, such as target coverage, dose conformity, and organs at risk (OARs) doses. Also, the treatment delivery parameters, including monitor units (MU), modulation factor (MF), and beam on time (BOT) were analyzed to assess the efficiency of each approach. The present study's findings revealed that both techniques achieved the constraints outlined in RTOG 0938. However, a statistically significant difference was observed between the two approaches. The full arc plans demonstrated superior target coverage, conformality, steeper dose gradient, and lower dose to femoral heads compared to the partial arc plans. On the other hand, the partial arc plans exhibited better sparing of the bladder and rectum. Also, the partial arc plans required fewer MU, resulting in a faster treatment time. Ultimately, the study concluded that the partial arc VMAT approach, utilizing a 10 MV flattening filter-free (FFF) beam, is the most effective technique for prostate SBRT, as it significantly enhances the sparing of organs at risk (OARs) and improves treatment delivery parameters. | ||||
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