Root Causes for Late Presentation of Severe Neonatal Hyperbilirubinemia

Mostafa, Mostafa Abdel-Azim; Elsayed, Rashad Abd Elhakim; Hawas, Shaimaa Soliman; El Taher, Sherif Mohamed; Afifi, Wesam El Menshawy

doi:10.21608/bjas.2025.341527.1544

	Root Causes for Late Presentation of Severe Neonatal Hyperbilirubinemia
Benha Journal of Applied Sciences
Article 6, Volume 9, Issue 12, December 2024, Page 47-52 PDF (305.01 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2025.341527.1544
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Authors
Mostafa Abdel-Azim Mostafa¹; Rashad Abd Elhakim Elsayed¹; Shaimaa Soliman Hawas ²; Sherif Mohamed El Taher³; Wesam El Menshawy Afifi⁴
¹Pediatrics, Faculty of Medicine - Benha University, Benha, Egypt
²M.B.B.Ch, Faculty of Medicine &ndash; Tanta University Department of of Pediatrics Faculty of Medicine - Benha University
³Pediatrics, Faculty of Medicine, Benha University, benha, egypt
⁴Pediatrics, Faculty of Medicine, Benha University, Benha, Egypt
Abstract
Hyperbilirubinemia (NH) in neonates is a frequent occurrence. NH is usually temporary and innocuous. Neonatals may, nevertheless, have kernicterus and encephalopathy in situations with severe NH. These negative aftereffects may be avoided with the right screening and care. Examining the social, cultural, educational, and systemic aspects of neonatal hyperbilirubinemia in newborns is the goal of this project. 350 patients with hyperbilirubinemia who were hospitalised to the Neonatal Intensive Care Unit in the Paediatric Department at Benha University Hospital, BENch at Benha, and Al Mabarra Insurance Hospital at Tanta were the subjects of this cross-sectional research. Every newborn had regular laboratory testing, a clinical examination, and a history. Total serum bilirubin (TSB) level and baby age (in hours) had a very statistically significant positive connection (rho = 0.561, P = 0.000). Higher gestational age, higher birth weight, greater reticulocyte count, and longer age (hours) were all significant positive predictors of higher TSB level (p < 0.05) in univariant analysis. Conversely, a higher TSB level was significantly predicted by a lower haemoglobin level. Age (hours), gestational age (weeks), and reticulocyte count were all revealed to be significant predictors of elevated TSB level in the multivariant analysis (F=37.7, p=0.000).
Keywords
Neonatal Jaundice; severe; late presentation


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