The Role of Transthoracic Ultrasound-Guided Tru-Cut Biopsy in the Diagnosis of Peripheral Lung Lesions | ||||
Benha Medical Journal | ||||
Article 7, Volume 42, Issue 7, July 2025, Page 751-763 PDF (722.11 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bmfj.2024.340528.2268 | ||||
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Authors | ||||
Hesham El-Sayed EL-Sheikh1; Osama Zain El-Din Mohamed2; Mohamed Abdel-Mohsen El-Mahdy3; Maram Ahmed EL-Gazzar ![]() | ||||
1Professor of Diagnostic and Interventional Radiology Department, Faculty of Medicine, Benha University | ||||
2Consultant of Diagnostic and Interventional Radiology, Military Medical Academy | ||||
3Professor of Chest Diseases, Faculty of Medicine, Benha University | ||||
4(MSc, Faculty of Medicine, Benha University) | ||||
Abstract | ||||
Background: Peripheral lung lesions, often indicative of various diseases, require accurate diagnosis for appropriate management. Ultrasound (US)-guided tru-cut biopsy offers a minimally invasive method for diagnosing these lesions. This study aims to evaluate the role of US-guided tru-cut biopsy in diagnosing peripheral lung lesions. Methods: This prospective study included 60 patients with imaging-confirmed peripheral lung masses, admitted to Benha University Hospitals between January and December 2023. All patients underwent US-guided tru-cut biopsy using a 16-gauge needle. Clinical and imaging data were collected, and histopathological analysis was performed. Results: The most common lesion sites were the right lower lobe (26.7%) and left upper lobe (23.3%). Bronchogenic carcinoma was the most prevalent pathology (66.6%), followed by malignant metastatic papillary adenocarcinoma (16.7%). Lesions larger than 5 cm were observed in 61.7% of cases. Solid masses with smooth margins were found in 43.3%. Two core biopsies were obtained in 96.7%, with 3.3% requiring a single core due to complications. Re-biopsy was needed in 6.7% of cases. Hydro pneumothorax occurred in 3.3%, requiring chest tube insertion. A significant association was found between core size and the need for re-biopsy (p=0.003), and pleural effusion and lung collapse were linked to complications (p=0.010). Conclusion: US-guided tru-cut biopsy is an effective, minimally invasive method for diagnosing peripheral lung lesions with minimal complications. Larger studies are needed to confirm these findings and explore its broader application. | ||||
Keywords | ||||
Peripheral Lung Lesions; Ultrasound; Tru-Cut Biopsy; Bronchogenic Carcinoma; Prospective Study | ||||
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