Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding
Salama Sieddek, A., Mohamed sayed, W., Nafady, S. (2025). Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding. EKB Journal Management System, 6(1), 35-51. doi: 10.21608/ejmr.2024.277897.1591
Asmaa Salama Sieddek; Walaa Mohamed sayed; Shaymaa Nafady. "Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding". EKB Journal Management System, 6, 1, 2025, 35-51. doi: 10.21608/ejmr.2024.277897.1591
Salama Sieddek, A., Mohamed sayed, W., Nafady, S. (2025). 'Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding', EKB Journal Management System, 6(1), pp. 35-51. doi: 10.21608/ejmr.2024.277897.1591
Salama Sieddek, A., Mohamed sayed, W., Nafady, S. Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding. EKB Journal Management System, 2025; 6(1): 35-51. doi: 10.21608/ejmr.2024.277897.1591

Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding

Egyptian Journal of Medical Research
Volume 6, Issue 1, January 2025, Pages 35-51    PDF (703.28 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2024.277897.1591
Authors
Asmaa Salama Sieddek* 1; Walaa Mohamed sayed2; Shaymaa Nafady3
1Lecturer of Hepatology, Gastroenterology and Infectious diseases. Beni-Suef University, Egypt
2Assistant lecturer of Hepatology, Gastroenterology and Infectious diseases, Faculty of Medicine, Beni Suef University, , Beni Suef, Egypt,
3Lecturer of Hepatology, Gastroenterology and Infectious diseases. Beni Suef University, Egypt
Abstract
Background:  Acute variceal bleeding as a cause of upper gastrointestinal tract hemorrhage is a serious problem that resulting in early death of cirrhotic patients. So, predicting the risk of early re-bleeding and death is crucial for preventing morbidity and mortality. Nowadays , there are multiple scoring systems with good prognostic power  have been developed, but there  is still a need  to find an easier and better scores that can be applied in clinical practice within each population and country. Aim: evaluation of the role of ALBI and PALBI scores as a prognostic tools in cirrhotic patients with variceal bleeding. Methodology: cross-sectional prospective study , done on patients admitted to Hepatology, Gastroenterology and Infectious diseases department at Beni-Suef University Hospital in Egypt who complained of acute onset of variceal bleeding. ALBI and PALBI were calculated and correlated with rates of hospital rebreeding and mortality.  Results: This study was done on 100 patients. The rates of first attack of bleeding, rebreeding and in-hospital mortality were 43 patients (43%), 37patients (37%) and 20 patients (20%). Age was a significant risk factor for in hospital morbidity and mortality (P= 0.008*) . Hb, WBCs, PLTs, Creatinine, liver enzymes (AST, ALT) and Bilirubin (T, D) had a statically significant relation to re-bleeding. Regarding hospital mortality,  ALBI , PALBI and MELD scores  have a better  prognostic value in prediction of mortality with  AUC  0.726, 0.798  and  0.750  respectively. Conclusion: ALBI, PALBI and MELD scores were helpful for prediction of hospital mortality in patients with variceal bleeding.
Keywords
Cirrhosis; Albumin Bilirubin; Platelet albumin bilirubin; Variceal bleeding
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