Biochemical Studies on the Effects of Collagen and Nucleotides on Growth of Broiler chickens | ||||
| Egyptian Journal of Veterinary Sciences | ||||
| Articles in Press, Corrected Proof, Available Online from 21 January 2025 PDF (851.55 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejvs.2025.335440.2485 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ibtehal Hashem Mahmoud Soliman  ; Magdy M. Youssef; Manar Refaat
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| Chemistry Department, Faculty of Science, Mansoura University, Egypt | ||||
| Abstract | ||||
| This study was designed to evaluate the effect of collagen and nucleotides as feed additives alone or in a combination on the growth performance, biochemical, hematological parameters, immune, antioxidant status and intestinal histomorphology in broiler chickens. A total of 60 one-day-old unsexed broiler chicks (Ross 308) were divided into four groups, each group included 15 chicks fed with different formulated diets for a period of 35 days. G1 was the control group and was fed basal diet only, G2 was fed basal diet with nucleotides (0.5 g/Kg feed), G3 was fed basal diet with collagen (100 mg/kg feed) and G4 was fed basal diet with a combination of nucleotide 0.5 g/Kg feed and collagen 100 mg/Kg feed. The obtained results showed that birds in the G2, G3 and G4 groups had significantly (p<0.05) higher body weight than control group. Nucleotides and collagen significantly improved feed conversion ratios in all treatments. Addition of nucleotides and collagen to broiler diets significantly (p<0.05) increased the blood levels of total leucocytes, erythrocytes, hemoglobin and hematocrit, also, increased the serum level of total proteins mainly globulin, uric acid, creatinine, triglycerides, GPx, SOD and Newcastle virus antibody titer, while decreased cholesterol, high-density lipoproteins, low-density lipoproteins, MDA and total antioxidant capacity. Nucleotides and nucleotides with collagen groups showed an improvement in intestinal histomorphology. Inclusion of collagen to broiler chickens diet significantly (p<0.05) increased the level of serum thrombocytes. In conclusion, the results demonstrated an enhancement in growth performance, hematological parameters, immunity, antioxidant status and intestinal histomorphology of broiler chickens by providing their diet with collagen and nucleotides. | ||||
| Keywords | ||||
| Broiler chickens; nucleotides; collagen; growth performance; immunity; intestinal histomorphology | ||||
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