Role of High Intensity Focused Ultrasound ( HIFU ) in Management of Uterine Fibroids | ||
| Benha Medical Journal | ||
| Article 2, Volume 42, Issue 6, June 2025, Pages 10-16 PDF (773.17 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.304580.2131 | ||
| Authors | ||
| Hesham Elsayed Elsheikh1; Mohammed Mohsen Fawzi2; Maged Maher Hanna* 3; Sherif Ahmed Elrefai Abdalsattar4 | ||
| 1Professor and Head of diagnostic and interventional radiology department Faculty of medicine - University of Benha | ||
| 2Consultant and Head of diagnostic and interventional radiology department National Hepatology and Tropical Medicine Research institute | ||
| 3MSc in diagnostic and interventional radiology | ||
| 4Lecturer of diagnostic and interventional radiology Faculty of medicine - University of Benha | ||
| Abstract | ||
| Background and Objective: Uterine fibroids are common benign gynecological tumors affecting women worldwide. This study aims to assess the effectiveness of High-Intensity Focused Ultrasound (HIFU) on uterine fibroid ablation, regarding fibroid volume at 3- and 6-months post-procedure. Methods: A prospective observational study was conducted at the National Hepatology and Tropical Medicine Research Institute. Thirty patients with uterine fibroid-related symptoms were included, and HIFU ablation was performed. Pre- and post-procedure assessments were carried out through comprehensive patient history, laboratory investigations, and post-contrast MRI examinations. Fibroid volume reduction and changes in pain levels and menorrhagia symptoms were analyzed. Results: HIFU ablation resulted in a significant reduction in pain levels (median score decreased from 6 to 3.5). No significant changes in hemoglobin levels were observed. Most participants experienced an improvement in menorrhagia symptoms (83.33%). Analysis of non-perfused volume (NPV) indicated successful ablation, with a mean NPV percent of 46.1%. Target fibroid volume significantly decreased at the 3-month and 6-month follow-ups, demonstrating the effectiveness of HIFU ablation in reducing fibroid size. The incidence of adverse events associated with HIFU ablation was low, with minimal complications reported. Conclusion: HIFU ablation emerges as a promising non-invasive treatment option for uterine fibroids, providing an effective reduction in fibroid volume, alleviation of symptoms, and minimal adverse events. Further long-term investigations are warranted to validate these findings and establish HIFU as a standard therapeutic approach for uterine fibroids. | ||
| Keywords | ||
| High-Intensity Focused Ultrasound (HIFU); Uterine fibroids; Ablation; Fibroid volume reduction; Non-invasive treatment | ||
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