Assessment of Glycated Albumin in Patient with Acute Coronary Syndromes and Its Correlation with Short Term Outcomes | ||
| Medicine Updates | ||
| Volume 22, Issue 22, July 2025, Pages 25-44 PDF (1.21 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/muj.2025.352077.1201 | ||
| Authors | ||
| Sohil Abdalla Ahmed Elfar1; Mohamed Fekry Hewedy* 2; Azza Zakaria El Eraky3; Mahmoud Shehata Abdelhamid4 | ||
| 1Associate Professor of Cardiovascular medicine, Faculty of Medicine, Port Said University, Egypt | ||
| 2Cardiovascular Resident, Ras El Bar Day-Case Hospital, Damietta, Egypt. | ||
| 3Professor of Cardiovascular Medicine, Faculty of Medicine, Port Said University | ||
| 4Lecturer of Cardiovascular medicine, Faculty of Medicine, Port Said University, Egypt | ||
| Abstract | ||
| Background: Acute coronary syndrome constitutes a major global health burden, significantly contributing to morbidity and mortality. While glycated albumin (GA) has emerged as a promising indicator of glycemic control, its prognostic value in patients experiencing ACS remains unclear. Aim of the Study: This study aims to investigate the association between glycated albumin levels and short-term complications in patients with acute coronary syndrome, considering clinical, biochemical, and echocardiographic characteristics. Materials and Methods: The study included 100 patients admitted to the Damietta Cardiology Gastroenterology Center with acute coronary syndrome from January 2022 to June 2023. Patients were divided into two groups: those with complications and those without. Data were collected on clinical, biochemical, and echocardiographic factors, including glycated albumin levels, ejection fraction, SYNTAX score, and complications. The predictive value of glycated albumin was analyzed using receiver operating characteristic curve analysis. Results: Elevated glycated albumin levels were significantly associated with complications especially cardiogenic shock. A glycated albumin level of 13.7% was identified as a cutoff for predicting worse clinical outcomes. Multivariate analysis revealed hypertension and lower ejection fraction as independent risk factors for complications. However, glycated albumin was not a significant predictor after adjusting for other variables. Conclusion: Glycated albumin is a promising biomarker for predicting complications in acute coronary syndrome patients. Although it was associated with short-term complications in univariate analysis, hypertension and lower ejection fraction were the primary independent risk factors for complications, suggesting that glycated albumin may not provide additional predictive value when adjusting for other clinical factors. | ||
| Keywords | ||
| Acute coronary syndrome; Complications; Glycated albumin; Risk stratification | ||
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